Next departures for Phoenix to San Diego on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Phoenix E Jefferson St
Cross Border Xpress CBX (USA)
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Phoenix Bus Station
UCSD Health La Jolla Station
No tags
Bus
Phoenix Bus Station
Greyhound Bus Stop
No tags
Bus
Phoenix E Jefferson St
Cross Border Xpress CBX (USA)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Phoenix Bus Station
Downtown SD (Seaport)
No tags
Next departures for Phoenix to San Diego on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Phoenix Bus Station
Greyhound Bus Stop
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
Greyhound Bus Stop
No tags
Bus
Phoenix E Jefferson St
Cross Border Xpress CBX (USA)
No tags
Next departures for Phoenix to San Diego on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Phoenix Bus Station
Greyhound Bus Stop
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
Greyhound Bus Stop
No tags
Bus
Phoenix E Jefferson St
Cross Border Xpress CBX (USA)
No tags
Next departures for Phoenix to San Diego on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Phoenix Bus Station
Greyhound Bus Stop
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
Greyhound Bus Stop
No tags
Bus
Phoenix E Jefferson St
Cross Border Xpress CBX (USA)
No tags
Next departures for Phoenix to San Diego on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Phoenix Bus Station
Greyhound Bus Stop
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
Greyhound Bus Stop
No tags
Bus
Phoenix E Jefferson St
Cross Border Xpress CBX (USA)
No tags
Next departures for Phoenix to San Diego on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Phoenix E Jefferson St
Cross Border Xpress CBX (USA)
Cheapest
Bus
Phoenix Bus Station
UCSD Health La Jolla Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
Greyhound Bus Stop
No tags
Next departures for Phoenix to San Diego on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
Cheapest
Bus
Phoenix Bus Station
UCSD Health La Jolla Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
Greyhound Bus Stop
No tags
Next departures for Phoenix to San Diego on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Phoenix Bus Station
Greyhound Bus Stop
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Phoenix Bus Station
Greyhound Bus Stop
No tags
Bus
Phoenix E Jefferson St
Cross Border Xpress CBX (USA)
No tags
Last refresh of the prices: Today at 8:24 AM MST.
Compare 2 ways to go from Phoenix to San Diego
We recommend taking the shuttle
Among the sustainable travel choices, the shuttle stands out as the good way to reach San Diego. The journey takes about 7 hours 10 minutes and with fares starting at just $138, it presents an excellent value for a comfortable ride.
Based on 266 reviews, the company was rated 3.4 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. Los Limousines ticket prices on this trip start at $96
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Lines, Inc. Phoenix San Diego recent customer reviews
I enjoyed the ride although the seats are a little hard and we got stopped by border patrol.. other than that it was okay.
4 out of 5 stars
Faustina M.
The only problem I had was the restroom on the bus had a very bad smell and no tissue to clean yourself.
4 out of 5 stars
Ophelia M.
Never going with them agaim. Bus from Phoenix to LA was late, so we didn’t catch the bus to San Diego. The only thing they could do was to give a new ticket to the bus leaving 3 hours later (But they couldn’t confirm there were enough seats for us). Very bad experience. I expect that Greyhound are going to fix the mistakes they did. It is not my fault I was 2 hours late. I feel it is a very bad deal for me to just sit there and wait another 3 hours without getting anything in return.
Frequently asked questions about traveling from Phoenix, AZ to San Diego, CA, US by bus
What is the travel distance from Phoenix to San Diego?
The distance separating Phoenix and San Diego is 299 miles (482 km).
What are the departure and arrival stations when taking the bus from Phoenix to San Diego?
The majority of buses traveling from Phoenix to San Diego start their journey at N 27th Ave and wind up at Mission Valley Sheraton. These are the most popular pick-up and drop-off locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in San Diego?
Once in San Diego, you can start exploring the city and discover its surroundings. The top sights and things to do are Pacific Surf School, Old Town, Cabrillo National Monument, San Diego Zoo and Old Point Loma Lighthouse.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$93
11/20
$93
Today
$83
11/22
$58
11/23
$58
11/24
$56
11/25
$58
11/26
$93
The cheapest trip from Phoenix, AZ to San Diego, CA, US was searched and found on Nov 24, 2025 with a price of $56
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Phoenix, AZ to San Diego, CA, US, as early as possible.
You can expect to pay from $56 to $172 for a bus ticket from Phoenix, AZ to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $56 which is on 2025-11-24.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Phoenix, AZ to San Diego, CA, US was searched and found on Nov 24, 2025 with a price of $56
