Find cheap bus tickets from Chicago to Knoxville

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TodayApr 27
from $79
TomorrowApr 28
from $96
MonApr 29
TueApr 30
WedMay 1
ThuMay 2
FriMay 3
SatMay 4

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: April 27 at
    Departure city: Chicago
    Departure location: Chicago 95Th & Dan Ryan
    Arrival time: April 28 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
    $79
  • This trip is recommended because it is: 2nd Cheapest
    Departure time: April 27 at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: April 28 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
    $191
  • Departure time: April 27 at
    Departure city: Chicago
    Departure location: Union Station
    Arrival time: April 28 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
    $191
Bus Chicago to Knoxville: Trip Overview

Bus Chicago to Knoxville: Trip Overview

Average ticket price$97
Average bus trip duration18h 35m
Number of daily buses5
Earliest bus departure2:00 AM
Distance453 miles (730 km)
Latest bus departure11:05 PM

Chicago to Knoxville Buses

Information on this bus route

Daily Departures5
Earliest and Latest Bus Departures2:00AM - 11:05PM
Minimum Price$66
Average Ticket Price$97
Minimum Trip Duration14h55m
Average Bus Trip Duration18h35m
Distance453 miles (730 km)
Bus Companies on This RouteGreyhound, FlixBus
Frequently Asked Questions

Frequently asked questions for your trip Chicago - Knoxville

The bus is the best choice to get to Knoxville without flying. The bus trip is an affordable, safe and convenient way to travel between the two cities. Alternatively, you can also use carpooling services.

The travel time from Chicago to Knoxville is about 18h 35m, but the quickest bus can get you there in about 14h 55m. This is the time it takes to travel the 454 miles (731 km) that separate the two cities.

About 454 miles (731 km) separate Chicago and Knoxville.

You can choose from 5 travel times and travel with Greyhound and FlixBus. The number of buses from Chicago to Knoxville can differ depending on the day of the week. Simplify your trip from Chicago to Knoxville by checking the schedules and selecting the bus that fits your travel style and budget on Busbud.

The bus service has you covered with departures starting at 2:00 AM and ending at 11:05 PM.

If you're headed to Knoxville from Chicago, chances are that your bus will leave from Downtown Greyhound Station and arrive at 100 Kirkwood St. These are the primary departure and arrival locations on this route, but you can also find other options that could better fit your plans.

The cheapest way to travel this route is by bus. $66 is the starting point for the cost-effective bus ride to Knoxville from Chicago.

The average price of a one-way ticket from Chicago to Knoxville is $97. In the last 30 days, the prices ranged from $66 to $265, so it's good to do your research before booking.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Chicago and Knoxville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Chicago to Knoxville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Chicago to Knoxville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to Knoxville.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Chicago by bus?

Bus from Knoxville to Chicago

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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.