What is the travel distance from Cincinnati to Syracuse?

The distance separating Cincinnati and Syracuse is 509 miles (820 km).

What are the departure and arrival stations when taking the bus from Cincinnati to Syracuse?

The majority of buses traveling from Cincinnati to Syracuse start their journey at Greyhound Station and wind up at Regional Transportation Center. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in Syracuse?

Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are MOST, Oncenter War Memorial Arena, Carrier Dome, Webster Pond and Rosamond Gifford Zoo.

Bus Cincinnati to Syracuse from $166 | Refundable Tickets

Previously seen trips

Next departures for Cincinnati to Syracuse on November 22
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	Bus	10:00am	Cincinnati (Downtown)	1d 7h	5:25pm	Syracuse (Regional Transportation Center)	No tags
	Bus	9:55am	Cincinnati Bus Station	1d 1h	11:45am	Syracuse (Regional Transportation Center)	No tags
	Bus	9:55am	Cincinnati Bus Station	1d 1h	11:45am	Syracuse (Regional Transportation Center)	No tags
FlixBus + Greyhound	Bus	9:40am	Cincinnati (Downtown)	1d 7h	5:25pm	Syracuse (Regional Transportation Center)	No tags
	Bus	4:40am	Cincinnati Bus Station	15h 45m	8:25pm	Syracuse (Regional Transportation Center)	No tags

Compare 2 ways to go from Cincinnati to Syracuse

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Syracuse. The journey takes about 16 hours 5 minutes and with fares starting at just $88, it presents an excellent value for a comfortable ride.

1bus per day

16h 5mAverage Duration

506 milesDistance

20kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$88 - $202	Average Duration16h 5m	CO₂ emissions 20kg CO₂e
Train	Average Price$237 - $309	Average Duration1d 9h	CO₂ emissions 75kg CO₂e

Where are the popular stops in Cincinnati and Syracuse?

Stops in Cincinnati

A
Greyhound Station
1005 Gilbert Ave, Cincinnati, OH 45202
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B
Northland Blvd
290-322 Northland Blvd, Springdale, OH 45246, USA

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Compare bus companies

Greyhound

3.5/587,388 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Cincinnati to Syracuse, US by bus

What is the travel distance from Cincinnati to Syracuse?
What are the departure and arrival stations when taking the bus from Cincinnati to Syracuse?
What are the best sights and things to do in Syracuse?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/20

No data

11/21

$141

Today

No data

11/23

No data

11/24

No data

11/25

$166

11/26

No data

11/27

No data

The cheapest trip from Cincinnati to Syracuse, US was searched and found on Nov 21, 2025 with a price of $141

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cincinnati to Syracuse, US, as early as possible.

You can expect to pay from $141 to $166 for a bus ticket from Cincinnati to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $166 which is on 2025-11-25.