Bus from Philadelphia, PA to Des Moines: Tickets & Schedules

Next bus departures

Next departures for Philadelphia to Des Moines on January 8
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Philadelphia, 199 Spring Garden St
Des MoinesCheapest
Greyhound Lines, Inc.Bus
199 Spring Garden St.
Des MoinesFastest
FlixBus + Greyhound Lines, Inc.
Bus
Cherry Hill Mall
Des MoinesNo tags
Greyhound Lines, Inc.Bus
Schuylkill & Walnut
Des MoinesNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Frazer - 56-40 Matthews Rd
Des MoinesNo tags

Last refresh of the prices: Last Monday at 7:55 AM EST.

Get from Philadelphia to Des Moines

This route is served by bus only

The journey takes about 1 day, 6 hours 10 minutes and with fares starting at just $171, it presents an excellent value for a comfortable ride.

7bus per day
1d 6hAverage Duration
948 milesDistance
38kgCO₂ emissions

Frequently asked questions about traveling from Philadelphia, PA to Des Moines by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Philadelphia to Des Moines?

    The cheapest bus tickets from Philadelphia to Des Moines start from $171. The average price for this route is around $247. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Philadelphia to Des Moines?

    The average bus trip duration from Philadelphia to Des Moines is 1d 6h, covering a distance of 948 miles (1528 km). The quickest bus can get you there in 1d 2h and is operated by Greyhound.

  3. Which bus companies service the Philadelphia to Des Moines route?

    Several major bus companies operate on this route with 7 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Philadelphia to Des Moines?

    The earliest bus departs from Philadelphia to Des Moines at 7:10am. And the latest bus departs at 8:15pm.

  5. What are the CO₂ emissions for the bus trip from Philadelphia to Des Moines?

    A bus trip from Philadelphia to Des Moines generates an estimated 38 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Philadelphia to Des Moines?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.

  7. Which bus company has the best Wi-Fi from Philadelphia to Des Moines?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Philadelphia to Des Moines?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Philadelphia to Des Moines?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/05
$199
01/06
$169
Today
No data
01/08
$165
01/09
$169
01/10
No data
01/11
$196
01/12
No data
busbud logoThe cheapest trip from Philadelphia, PA to Des Moines was searched and found on Jan 8, 2026 with a price of $165

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Des Moines, as early as possible.

You can expect to pay from $165 to $241 for a bus ticket from Philadelphia, PA to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $165 which is on 2026-01-08.

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