Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Knoxville Bus Station | Lankershim/Magnolia - North Hollywood | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Knoxville Bus Station | Los Angeles Union Station | Fastest | ||||
| Bus | Knoxville Bus Station | Los Angeles Union Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Knoxville Bus Station | Downtown LA (Flixbus Lot) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Knoxville Bus Station | Downtown LA (Flixbus Lot) | No tags |
Last refresh of the prices: Last Saturday at 10:21 PM EST.
Get from Knoxville to Los Angeles
The journey takes about 2 days, 1 hour 40 minutes and with fares starting at just $156, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Los Angeles?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Los Angeles
- A571-581 Gayley Ave, Los Angeles, CA 90024, USA
- B
Ramirez Street bus stop
530 Ramirez St, Los Angeles, CA 90012, USA - C613 Maple Ave, Los Angeles, CA 90014, USA
- E
Downtown Westin Bonaventure
404 S Figueroa St, Los Angeles, CA 90071, USA - F
LAX Airport Holiday Inn
9901 S La Cienega Blvd, Los Angeles, CA 90045, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Knoxville, TN to Los Angeles, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Knoxville to Los Angeles?
The cheapest bus tickets from Knoxville to Los Angeles start from $156. The average price for this route is around $296. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Knoxville to Los Angeles?
The average bus trip duration from Knoxville to Los Angeles is 2d 1h, covering a distance of 1935 miles (3120 km). The quickest bus can get you there in 2d 1h and is operated by Greyhound.
Which bus companies service the Knoxville to Los Angeles route?
Several major train operators operate on this route with 6 trains available per day.
What is the earliest and latest departure time for the bus from Knoxville to Los Angeles?
The earliest bus departs from Knoxville to Los Angeles at 6:10pm. And the latest bus departs at 7:40pm.
What are the CO₂ emissions for the bus trip from Knoxville to Los Angeles?
A bus trip from Knoxville to Los Angeles generates an estimated 78 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Los Angeles, US was searched and found on Jan 22, 2026 with a price of $217To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Los Angeles, US, as early as possible.
You can expect to pay from $217 to $236 for a bus ticket from Knoxville, TN to Los Angeles, US based on the last 2 days. You can expect to find the cheapest price for the trip at $217 which is on 2026-01-22.
