How much is the bus ticket from Lafayette to San Diego?

The cheapest bus tickets from Lafayette to San Diego start from $146. The average price for this route is around $509. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Lafayette to San Diego?

The average bus trip duration from Lafayette to San Diego is 2d 1h, covering a distance of 1486 miles (2396 km). The quickest bus can get you there in 1d 16h and is operated by Greyhound .

Which bus companies service the Lafayette to San Diego route?

Several major bus companies operate on this route with 19 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Lafayette to San Diego?

The earliest bus departs from Lafayette to San Diego at 3:15am. And the latest bus departs at 10:10pm.

What are the CO₂ emissions for the bus trip from Lafayette to San Diego?

A bus trip from Lafayette to San Diego generates an estimated 60 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Lafayette to San Diego?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87463 reviews.

Which bus company has the best Wi-Fi from Lafayette to San Diego?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Lafayette to San Diego?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Lafayette to San Diego?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Lafayette to San Diego from $144 | Refundable Tickets

Next bus departures

Next departures for Lafayette to San Diego on January 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	9:20pm	Lafayette Transit System	1d 18h	2:10pm	San Diego (Old Town-FlixBus)	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	9:20pm	Lafayette Transit System	1d 18h	1:40pm	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	10:10pm	Lafayette Transit System	1d 22h	6:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	12:20pm	Lafayette Transit System	2d 1h	11:45am	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	12:20pm	Lafayette Transit System	1d 23h	9:40am	UCSD Health La Jolla Station	No tags

Last refresh of the prices: Last Wednesday at 8:11 AM CST.

Compare 2 ways to go from Lafayette to San Diego

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as the good way to reach San Diego. The journey takes about 2 days, 1 hour 55 minutes and with fares starting at just $146, it presents an excellent value for a comfortable ride.

19bus per day

2d 1hAverage Duration

1486 milesDistance

60kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$146 - $732	Average Duration2d 1h	CO₂ emissions 60kg CO₂e
Train	Average Price$343 - $1,320	Average Duration1d 23h	CO₂ emissions 218kg CO₂e

Where are the popular stops in Lafayette and San Diego?

Stops in Lafayette

A
TA Travel Center - Lafayette
1701 N University Ave, Lafayette, LA 70507, USA
Visit page Map
B
Lafayette A and J Travel Bus Station
100 Lee Ave, Lafayette, LA 70501
Map
C
Lafayette Bus Stop
2405 Cameron St, Lafayette, LA, USA
Map

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
Map
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
Map
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
Map
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
Map
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
Map
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Map

Compare bus companies

Greyhound

3.5/587,492 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,987 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Lafayette, LA to San Diego, CA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Lafayette to San Diego?
The cheapest bus tickets from Lafayette to San Diego start from $146. The average price for this route is around $509. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lafayette to San Diego?
The average bus trip duration from Lafayette to San Diego is 2d 1h, covering a distance of 1486 miles (2396 km). The quickest bus can get you there in 1d 16h and is operated by Greyhound.
Which bus companies service the Lafayette to San Diego route?
Several major bus companies operate on this route with 19 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Lafayette to San Diego?
The earliest bus departs from Lafayette to San Diego at 3:15am. And the latest bus departs at 10:10pm.
What are the CO₂ emissions for the bus trip from Lafayette to San Diego?
A bus trip from Lafayette to San Diego generates an estimated 60 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Lafayette to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Lafayette to San Diego?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Lafayette to San Diego?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Lafayette to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/08

No data

01/09

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Today

$316

01/11

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01/12

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01/13

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01/14

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01/15

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The cheapest trip from Lafayette, LA to San Diego, CA, US was searched and found on Jan 10, 2026 with a price of $316

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, LA to San Diego, CA, US, as early as possible.