Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Pueblo Transit | San Antonio Bus Station | CheapestFastest |
Last refresh of the prices: 02/08/2026 MST.
Get from Pueblo to San Antonio
The journey takes about 19 hours 5 minutes and with fares starting at just $95, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pueblo and San Antonio?
Stops in Pueblo
- A
Pueblo Transit Bus Station
123 Court St, Pueblo, CO 81003
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C4407 S PanAm Expy #101, San Antonio, TX 78225, USA
- D165 Bowie St, San Antonio, 78205
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Pueblo to San Antonio, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Pueblo to San Antonio?
The cheapest bus tickets from Pueblo to San Antonio start from $95. The average price for this route is around $131. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pueblo to San Antonio?
The average bus trip duration from Pueblo to San Antonio is 19h 5m, covering a distance of 703 miles (1134 km). The quickest bus can get you there in 19h 5m and is operated by Greyhound.
Which bus companies service the Pueblo to San Antonio route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Pueblo to San Antonio?
The earliest bus departs from Pueblo to San Antonio at 10:25pm. And the latest bus departs at 10:25pm.
What are the CO₂ emissions for the bus trip from Pueblo to San Antonio?
A bus trip from Pueblo to San Antonio generates an estimated 28 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pueblo to San Antonio, US was searched and found on Feb 15, 2026 with a price of $105To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pueblo to San Antonio, US, as early as possible.
You can expect to pay from $105 to $157 for a bus ticket from Pueblo to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at $105 which is on 2026-02-16.
