Bus Tickets from Roanoke to Chicago

Next departures

Next departures for Roanoke to Chicago on October 10
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Roanoke Bus Stop
Downtown Greyhound StationCheapest
Greyhound Lines, Inc.
Roanoke Bus Stop
537-517 W. Jackson BlvdFastest
Greyhound Lines, Inc. + FlixBus
Roanoke Bus Stop
Downtown Greyhound StationNo tags
Greyhound Lines, Inc. + FlixBus
Roanoke Bus Stop
Chicago 95Th & Dan RyanNo tags
Greyhound Lines, Inc. + FlixBus
Roanoke Bus Stop
Chicago 95Th & Dan RyanNo tags

Last refresh of the prices: Yesterday at 9:20 PM EDT.

Accepted payments

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Compare 2 ways to go from Roanoke to Chicago.

Bus
Average Price$87 - $366Average Duration22h
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$135 - $310Average Duration1d 3h
76kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Roanoke to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 22 hours and with fares starting at just $87, it presents an excellent value for a comfortable ride.

4bus per day
22hAverage Duration
$87Cheapest ticket
21kgCO₂ emissions

Bus Roanoke to Chicago: Trip Overview

Average ticket price$160
Average bus trip duration22h
Number of daily buses4
Earliest bus departure4:35am
Distance511 miles (823 km)
Latest bus departure12:50pm

Roanoke to Chicago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Roanoke to Chicago.

Bus service from Roanoke to Chicago will be provided by the most trusted bus companies.

Discover how much the bus trip from Roanoke to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Roanoke - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/06
$152
10/07
$153
Today
$245
10/09
No data
10/10
$124
10/11
No data
10/12
No data
10/13
No data
busbud logoThe cheapest trip from Roanoke to Chicago was searched and found on Oct 10, 2025 with a price of $124

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Roanoke to Chicago, as early as possible.

You can expect to pay from $124 to $245 for a bus ticket from Roanoke to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $124 which is on 2025-10-10.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Roanoke to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Roanoke to Chicago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Roanoke to Chicago will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Roanoke to Chicago while indulging in miles on end of beautiful scenic views.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

What's the cheapest way to go from Roanoke to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Roanoke by bus?

Bus from Chicago to Roanoke

You can also go to Chicago by train

Train from Roanoke to Chicago

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