Bus Tickets from Salem, OR, US to San Diego, CA, US

Find affordable bus tickets from Salem, OR, US to San Diego, CA, US with flexible options. Book your trip now

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TodayJun 26
from $155
TomorrowJun 27
from $131
SatJun 28
from $153
SunJun 29
from $225
MonJun 30
TueJul 1
from $130
WedJul 2
from $138
ThuJul 3

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: June 27 at
    Departure city: Salem
    Departure location: Liberty St SE
    Arrival time: June 28 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 27 at
    Departure city: Salem
    Departure location: Liberty St SE
    Arrival time: June 29 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 27 at
    Departure city: Salem
    Departure location: Liberty St SE
    Arrival time: June 29 at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Salem to San Diego.

Average Price$96 - $252Average Duration1d 18h
36kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average Price$149 - $282Average Duration1d 9h
131kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Salem to San Diego

Among the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 1 day, 9 hours 11 minutes and with fares starting at just $149, it presents an excellent value for a comfortable ride.

5train per day
1d 9hAverage Duration
$149Cheapest ticket
131kgCO₂ emissions

Bus Salem to San Diego: Trip Overview

Average ticket price$144
Average bus trip duration1d 18h
Number of daily buses3.4799999999999995
Earliest bus departure9:10pm
Distance888 miles (1431 km)

Salem to San Diego Bus

Busbud helps you find a bus from Salem to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Salem to San Diego will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to San Diego from Salem, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Salem, OR, US - San Diego, CA, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/24
$214
06/25
No data
Today
No data
06/27
No data
06/28
No data
06/29
No data
06/30
No data
07/01
No data
busbud logoThe cheapest trip from Salem to San Diego was searched and found on Jun 24, 2025 with a price of $214

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salem to San Diego, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Salem and San Diego!

Much more than a mere vehicle taking you from Salem to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Salem to San Diego.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Salem to San Diego.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Salem to San Diego?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Salem by bus?

Bus from Salem to San Diego

You can also go to San Diego by train

Train from Salem to San Diego

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