Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Santiago Tuxtla, Santiago Tuxtla Ver. | TAPO | CheapestFastest | ||||
| Bus | Santiago Tuxtla, Santiago Tuxtla Ver. | TAPO | No tags | ||||
| Bus | Santiago Tuxtla, Santiago Tuxtla Ver. | TAPO | No tags | ||||
| Bus | Santiago Tuxtla, Santiago Tuxtla Ver. | Terminal del Norte | No tags |
Last refresh of the prices: Today at 10:26 AM CST.
Get from Santiago Tuxtla to Mexico City
The journey takes about 9 hours 15 minutes and with fares starting at just $76, it presents an excellent value for a comfortable ride.
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Frequently asked questions about traveling from Santiago Tuxtla to Mexico City by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santiago Tuxtla to Mexico City?
The cheapest bus tickets from Santiago Tuxtla to Mexico City start from $76. The average price for this route is around $81. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santiago Tuxtla to Mexico City?
The average bus trip duration from Santiago Tuxtla to Mexico City is 9h 15m, covering a distance of 258 miles (416 km). The quickest bus can get you there in 8h 55m and is operated by ADO.
Which bus companies service the Santiago Tuxtla to Mexico City route?
What is the earliest and latest departure time for the bus from Santiago Tuxtla to Mexico City?
The earliest bus departs from Santiago Tuxtla to Mexico City at 9:20pm. And the latest bus departs at 11:40pm.
What are the CO₂ emissions for the bus trip from Santiago Tuxtla to Mexico City?
A bus trip from Santiago Tuxtla to Mexico City generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Santiago Tuxtla to Mexico City?
According to Busbud customers, the highest-rated bus company on this route is ADO, with an average rating of 4.2 out of 5 stars based on 9963 reviews.
Which bus company has the best Wi-Fi from Santiago Tuxtla to Mexico City?
Based on reviews on Busbud, the bus company ADO has the best Wi-Fi rating with a score of 2.0.
Which bus company has the most timely service from Santiago Tuxtla to Mexico City?
According to Busbud traveller reviews, the most timely bus company on this route is ADO, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Santiago Tuxtla to Mexico City?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ADO, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santiago Tuxtla to Mexico City was searched and found on Dec 9, 2025 with a price of $67To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago Tuxtla to Mexico City, as early as possible.
You can expect to pay from $67 to $71 for a bus ticket from Santiago Tuxtla to Mexico City based on the last 2 days. You can expect to find the cheapest price for the trip at $67 which is on 2025-12-09.
