Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | Detroit Bus Station | CheapestFastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Gateway Station | Detroit Bus Station | No tags | ||||
| Bus | Gateway Station | Detroit Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Gateway Station | Detroit Bus Station | No tags |
Last refresh of the prices: Yesterday at 10:47 AM CST.
Compare 2 ways to go from St. Louis to Detroit
Among the sustainable travel choices, the bus stands out as the good way to reach Detroit. The journey takes about 15 hours 15 minutes and with fares starting at just $65, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Detroit?
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from St. Louis to Detroit, MI by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Detroit, MI was searched and found on Dec 2, 2025 with a price of $75To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Detroit, MI, as early as possible.
You can expect to pay from $75 to $330 for a bus ticket from St. Louis to Detroit, MI based on the last 2 days. You can expect to find the cheapest price for the trip at $75 which is on 2025-12-02.
What's the cheapest way to go from St. Louis to Detroit, MI?
The bus is the cheapest travel choice for this destination
