Next departures for St. Louis to Orlando on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
The Florida Mall
Cheapest
Bus
Gateway Station
Orlando Bus Station
Fastest
Next departures for St. Louis to Orlando on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
Orlando Bus Station
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Gateway Station
Orlando Bus Station
No tags
Bus
Gateway Station
Orlando Bus Station
No tags
Bus
Gateway Station
The Florida Mall
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Gateway Station
Orlando Bus Station
No tags
Next departures for St. Louis to Orlando on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
The Florida Mall
Cheapest
Bus
Gateway Station
Orlando Bus Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Gateway Station
Orlando Bus Station
No tags
Bus
Gateway Station
Orlando Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Gateway Station
Orlando Bus Station
No tags
Next departures for St. Louis to Orlando on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Gateway Station
Orlando Bus Station
Cheapest
Bus
Gateway Station
Orlando Bus Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Gateway Station
Orlando Bus Station
No tags
Bus
Gateway Station
Orlando Bus Station
No tags
Bus
Gateway Station
The Florida Mall
No tags
Next departures for St. Louis to Orlando on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Gateway Station
The Florida Mall
Cheapest
Bus
Gateway Station
Orlando Bus Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Gateway Station
Orlando Bus Station
No tags
Bus
Gateway Station
Orlando Bus Station
No tags
Bus
Gateway Station
The Florida Mall
No tags
Next departures for St. Louis to Orlando on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Gateway Station
The Florida Mall
Cheapest
Bus
Gateway Station
Orlando Bus Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Gateway Station
Orlando Bus Station
No tags
Bus
Gateway Station
Orlando Bus Station
No tags
Bus
Gateway Station
The Florida Mall
No tags
Last refresh of the prices: Yesterday at 11:13 PM CST.
Compare 2 ways to go from St. Louis to Orlando
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Orlando. The journey takes about 1 day, 2 hours 35 minutes and with fares starting at just $102, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from St. Louis to Orlando by bus
What is the distance between St. Louis and Orlando?
The distance between the two cities is 861 miles (1388 km).
What are the departure and arrival stations when taking the bus from St. Louis to Orlando?
If you're headed to Orlando from St. Louis, chances are that your bus will depart from Gateway Station and arrive at Orlando Bus Station. These are the most popular departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Orlando?
Once in Orlando, you can start exploring the city and discover its surroundings. The top sights and things to do are Orlando Science Center and Dr. Phillips Cinedome, Orlando Wetlands Park, K1 Speed, Hard Rock Live and John F. Kennedy Space Center.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/20
$252
11/21
$198
Today
$198
11/23
$190
11/24
$142
11/25
$200
11/26
$199
11/27
$120
The cheapest trip from St. Louis to Orlando was searched and found on Nov 27, 2025 with a price of $120
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Orlando, as early as possible.
You can expect to pay from $120 to $345 for a bus ticket from St. Louis to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $120 which is on 2025-11-27.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from St. Louis to Orlando?
The bus is the cheapest travel choice for this destination