Bus from St. Louis to Philadelphia, PA: Tickets & Schedules
Next bus departures
Next departures for St. Louis to Philadelphia on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
199 Spring Garden St.
CheapestFastest
FlixBus + Greyhound Lines, Inc.
Bus
Gateway Station
199 Spring Garden St.
No tags
Bus
Gateway Station
Philadelphia, 199 Spring Garden St
No tags
Bus
Gateway Station
Camden (Walter Rand Transportation Center)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Gateway Station
Philadelphia, 199 Spring Garden St
No tags
Next departures for St. Louis to Philadelphia on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
199 Spring Garden St.
Cheapest
Bus
Gateway Station
199 Spring Garden St.
Fastest
Bus
Gateway Station
199 Spring Garden St.
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Gateway Station
199 Spring Garden St.
No tags
Bus
Gateway Station
Philadelphia, 199 Spring Garden St
No tags
Last refresh of the prices: Yesterday at 3:06 PM CST.
Compare 2 ways to go from St. Louis to Philadelphia
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Philadelphia. The journey takes about 1 day, 8 hours 15 minutes and with fares starting at just $91, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from St. Louis to Philadelphia, PA by bus
What is the travel distance from St. Louis to Philadelphia?
St. Louis and Philadelphia are 808 miles (1303 km) apart.
What are the departure and arrival stations when taking the bus from St. Louis to Philadelphia?
The majority of buses traveling from St. Louis to Philadelphia start their journey at Gateway Station and wind up at Philadelphia Airport. These are the most popular pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Philadelphia?
Once in Philadelphia, you can start exploring the city and discover its surroundings. The top sights and things to do are Eastern State Penitentiary, The Barnes Foundation, The Franklin Institute, Shofuso Japanese House and Garden and Love Park.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
$120
11/25
$173
Today
$173
11/27
$132
11/28
No data
11/29
No data
11/30
No data
12/01
No data
The cheapest trip from St. Louis to Philadelphia, PA was searched and found on Nov 24, 2025 with a price of $120
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Philadelphia, PA, as early as possible.
You can expect to pay from $120 to $284 for a bus ticket from St. Louis to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $132 which is on 2025-11-27.
What's the cheapest way to go from St. Louis to Philadelphia, PA?
The bus is the cheapest travel choice for this destination
The cheapest trip from St. Louis to Philadelphia, PA was searched and found on Nov 24, 2025 with a price of $120
The bus is the cheapest travel choice for this destination
