Next departures for Yuma to San Diego on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Yuma County Area Transit
San Diego (Old Town-FlixBus)
Cheapest
Bus
Yuma County Area Transit
UCSD Health La Jolla Station
Fastest
Bus
Yuma County Area Transit
Downtown SD (Seaport)
No tags
Next departures for Yuma to San Diego on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Yuma County Area Transit
UCSD Health La Jolla Station
CheapestFastest
Bus
Yuma County Area Transit
San Diego (Old Town-FlixBus)
No tags
Bus
Yuma County Area Transit
Downtown SD (Seaport)
No tags
Next departures for Yuma to San Diego on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Yuma County Area Transit
Greyhound Bus Stop
CheapestFastest
Next departures for Yuma to San Diego on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Yuma County Area Transit
Downtown SD (Seaport)
Cheapest
Bus
Yuma County Area Transit
UCSD Health La Jolla Station
Fastest
Bus
Yuma County Area Transit
San Diego (Old Town-FlixBus)
No tags
Last refresh of the prices: Yesterday at 10:35 PM MST.
Compare 3 ways to go from Yuma to San Diego
We recommend taking the shuttle
Among the sustainable travel choices, the shuttle stands out as the good way to reach San Diego. The journey takes about 3 hours 40 minutes and with fares starting at just $88, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Lines, Inc. Yuma San Diego recent customer reviews
It was on time
5 out of 5 stars
Leticia W.
The bus driver was most helpful and I really did appreciate her thoughtfulness.
5 out of 5 stars
Dianne E.
It was very unclear where I needed to go to get my ticket printed out.
Where are the popular stops in Yuma and San Diego?
Stops in Yuma
A - Yuma
1643-1713 S Sunridge Dr, Yuma, AZ 85365, USA
Stops in San Diego
A - Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B - Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C - Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D - Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E - Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F - San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Frequently asked questions about traveling from Yuma to San Diego, CA, US by bus
What is the distance between Yuma and San Diego?
Yuma and San Diego are 149 miles (240 km) apart.
What are the departure and arrival stations when taking the bus from Yuma to San Diego?
If you're headed to San Diego from Yuma, chances are that your bus will depart from Yuma and arrive at Mission Valley Sheraton. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in San Diego?
Once in San Diego, you can start exploring the city and discover its surroundings. The top sights and things to do are La Jolla Cove, Old Point Loma Lighthouse, Sunset Cliffs Natural Park, The Gaslamp Quarter and USS Midway Museum.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$33
11/18
$33
Today
$69
11/20
$66
11/21
$82
11/22
$36
11/23
No data
11/24
$35
The cheapest trip from Yuma to San Diego, CA, US was searched and found on Nov 17, 2025 with a price of $33
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Yuma to San Diego, CA, US, as early as possible.
You can expect to pay from $33 to $82 for a bus ticket from Yuma to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $35 which is on 2025-11-24.
What's the cheapest way to go from Yuma to San Diego, CA, US?
The bus is the cheapest travel choice for this destination
The cheapest trip from Yuma to San Diego, CA, US was searched and found on Nov 17, 2025 with a price of $33
The bus is the cheapest travel choice for this destination
