How much is the bus ticket from Baltimore to Florence?

The cheapest bus tickets from Baltimore to Florence start from $83. The average price for this route is around $140. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Baltimore to Florence?

The average bus travel time from Baltimore to Florence is 10h 10m, covering a distance of 630 km. The quickest bus can get you there in 8h 15m and is operated by FlixBus .

Which bus companies service the Baltimore to Florence route?

Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound , FlixBus , Wanda Coach .

What are the earliest and latest departure times for the bus from Baltimore to Florence?

The earliest bus departs from Baltimore to Florence at 1:35am. And the latest bus departs at 11:45pm.

What are the CO₂ emissions for the bus trip from Baltimore to Florence?

A bus trip from Baltimore to Florence generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Baltimore to Florence?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87387 reviews.

Which bus company has the best Wi-Fi from Baltimore to Florence?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from Baltimore to Florence?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Baltimore to Florence?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Baltimore to Florence from $72 | Refundable Tickets

Next bus departures

Next departures for Baltimore to Florence on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	11:10pm	O'Donnell St. & Travel Plaza, Infront of TA Gas station	8h 50m	8:00am	2301 W Lucas St.	CheapestFastest
	Bus	11:45pm	Baltimore Downtown Bus Station	12h	11:45am	Bus station	No tags
	Bus	8:30pm	Baltimore Downtown Bus Station	9h 15m	5:45am	Florence, SC	No tags
Greyhound Lines, Inc. + FlixBus	Bus	2:50pm	Baltimore Bus Stop	14h 55m	5:45am	Florence, SC	No tags

Next departures for Baltimore to Florence on November 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	11:10pm	O'Donnell St. & Travel Plaza, Infront of TA Gas station	8h 50m	8:00am	2301 W Lucas St.	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	1:35am	Baltimore Downtown Bus Station	10h 10m	11:45am	Bus station	No tags
	Bus	11:45pm	Baltimore Downtown Bus Station	12h	11:45am	Bus station	No tags
	Bus	8:30pm	Baltimore Downtown Bus Station	9h 15m	5:45am	Florence, SC	No tags
Greyhound Lines, Inc. + FlixBus	Bus	2:50pm	Baltimore Bus Stop	14h 55m	5:45am	Florence, SC	No tags

Next departures for Baltimore to Florence on December 3
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	11:45pm	Baltimore Downtown Bus Station	12h	11:45am	Bus station	Cheapest
	Bus	11:10pm	O'Donnell St. & Travel Plaza, Infront of TA Gas station	8h 50m	8:00am	2301 W Lucas St.	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	1:35am	Baltimore Downtown Bus Station	10h 10m	11:45am	Bus station	No tags
	Bus	8:30pm	Baltimore Downtown Bus Station	9h 15m	5:45am	Florence, SC	No tags
Greyhound Lines, Inc. + FlixBus	Bus	2:50pm	Baltimore Bus Stop	14h 55m	5:45am	Florence, SC	No tags

Last refresh of the prices: Yesterday at 4:33 AM EST.

Compare 2 ways to go from Baltimore to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 10 hours 10 minutes, and with fares starting at just $83, it presents an excellent value for a comfortable ride.

5bus per day

10h 10mAverage Duration

630 kmDistance

16kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$83 - $300	Average Duration10h 10m	CO₂ emissions 16kg CO₂e
Train	Average Price$112 - $395	Average Duration9h 12m	CO₂ emissions 58kg CO₂e

Where are the popular stops in Baltimore and Florence?

Stops in Baltimore

A
Baltimore Downtown Bus Station
2110 Haines St, Baltimore, MD 21230, United States
Visit page
B
Penn Station
7 St Paul St, Baltimore, MD 21201, USA
Visit page
C
Baltimore Airport
Visit page
D
Maryland Ave & I-83
1578 Maryland Ave, Baltimore, MD 21201, USA
Visit page

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

Greyhound

3.5/587,403 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/511,465 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Wanda Coach

2.5/5650 reviews

Staff3

Timeliness2.8

Cleanliness2.4

Wifi1.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Baltimore to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Baltimore to Florence?
The cheapest bus tickets from Baltimore to Florence start from $83. The average price for this route is around $140. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Baltimore to Florence?
The average bus travel time from Baltimore to Florence is 10h 10m, covering a distance of 630 km. The quickest bus can get you there in 8h 15m and is operated by FlixBus.
Which bus companies service the Baltimore to Florence route?
Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, FlixBus, Wanda Coach.
What are the earliest and latest departure times for the bus from Baltimore to Florence?
The earliest bus departs from Baltimore to Florence at 1:35am. And the latest bus departs at 11:45pm.
What are the CO₂ emissions for the bus trip from Baltimore to Florence?
A bus trip from Baltimore to Florence generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Baltimore to Florence?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Baltimore to Florence?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Baltimore to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Baltimore to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-26

$236

11-27

$144

Today

$144

11-29

$144

11-30

$144

12-01

No data

12-02

$88

12-03

$84

The cheapest trip from Baltimore to Florence, SC, US was searched and found on Dec 3, 2025 with a price of $84

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Baltimore to Florence, SC, US, as early as possible.

You can expect to pay from $84 to $313 for a bus ticket from Baltimore to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $84 which is on 2025-12-03.

Usually FlixBus, Wanda Coach will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.