Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Baltimore Downtown Bus Station | Florence, SC | Cheapest | ||||
 | Bus | O'Donnell St. & Travel Plaza, Infront of TA Gas station | 2301 W Lucas St. | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Baltimore Bus Stop | Florence, SC | No tags | ||||
 | Bus | Baltimore Downtown Bus Station | Bus station | No tags | ||||
| Bus | Baltimore Downtown Bus Station | Bus station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Baltimore Downtown Bus Station | Bus station | No tags |
Last refresh of the prices: Last Wednesday at 5:50 PM EDT.
Compare 2 ways to go from Baltimore to Florence
Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 9 hours 55 minutes, and with fares starting at just JP¥9,848, it presents an excellent value for a comfortable ride.
Bus stations and stops in Baltimore and Florence
Stops in Baltimore
- A
Baltimore Downtown Bus Station
2110 Haines St, Baltimore, MD 21230, United States - B
Penn Station
7 St Paul St, Baltimore, MD 21201, USA - C
Maryland Ave & I-83
1578 Maryland Ave, Baltimore, MD 21201, USA
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about travelling from Baltimore to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Baltimore to Florence?
The cheapest bus tickets from Baltimore to Florence start from JP¥9,848. The average price for this route is around JP¥14,756. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Baltimore to Florence?
The average bus travel time from Baltimore to Florence is 9h 55m, covering a distance of 631 km. The quickest bus can get you there in 8h 50m and is operated by Wanda Coach.
Which bus companies service the Baltimore to Florence route?
Several major bus companies operate on this route with 8 buses available per day, including services from Greyhound, FlixBus, Wanda Coach.
What are the earliest and latest departure times for the bus from Baltimore to Florence?
The earliest bus departs from Baltimore to Florence at 12:10am. And the latest bus departs at 11:25pm.
What are the CO₂ emissions for the bus trip from Baltimore to Florence?
A bus trip from Baltimore to Florence generates an estimated 15.76025 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Baltimore to Florence?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87579 reviews.
Which bus company has the best Wi-Fi from Baltimore to Florence?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Baltimore to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Baltimore to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Baltimore to Florence, SC, US was searched and found on Jul 20, 2026 with a price of JP¥9,318To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Baltimore to Florence, SC, US, as early as possible.
You can expect to pay from JP¥9,318 to JP¥27,543 for a bus ticket from Baltimore to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at JP¥9,318 which is on 2026-07-20.
Usually FlixBus, Wanda Coach will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Baltimore to Florence, SC, US?
The Bus is the cheapest travel choice for this destination
