Bus Tickets from Framingham, MA to St Louis, MO

Find affordable bus tickets from Framingham, MA to St Louis, MO with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Compare 2 ways to go from Framingham to St Louis

Average PriceUS$170 - US$214Average Duration1d 9h
41kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$303 - US$363Average Duration1d 11h
149kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Framingham to St Louis

Among the sustainable travel choices, the bus stands out as a good way to reach St Louis. The journey takes about 1 day, 9 hours 50 minutes, and with fares starting at just US$170, it presents an excellent value for a comfortable ride.

1bus per day
1d 9hAverage Duration
US$170Cheapest ticket
41kgCO₂ emissions

Bus Framingham to St Louis: Trip Overview

Average Ticket PriceUS$191
Average Bus Trip Duration1d 9h
Number of daily buses1
Earliest bus departure2:45pm
Distance1637 km

Framingham to St Louis Bus

Busbud helps you find a bus from Framingham to St Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Framingham to St Louis will be provided by the most trusted bus companies.

Discover how much the bus trip from Framingham to St Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Framingham - St Louis

  1. How long does it take to get to St Louis from Framingham by bus?

    The bus ride from Framingham to St Louis takes 1d 9h, on average. For the shortest travel time, select the fastest bus available, which will take you to St Louis in about 1d 9h.

  2. What is the distance between Framingham and St Louis?

    The distance between Framingham and St Louis is approximately 1638 km (1016 miles).

  3. What are the departure and arrival locations for buses traveling from Framingham to St Louis?

    Buses departing from Framingham Flutie Pass Bus Stop in Framingham will take you to Gateway Station in St Louis.

  4. What is the cheapest way to get from Framingham to St Louis?

    The least expensive way to go from Framingham to St Louis would be going by bus. Starting at US$170, this bus is the most cost-effective option for your journey.

  5. How much is the bus from Framingham to St Louis?

    You can expect to pay around US$191 for the bus ride from Framingham to St Louis.

  6. Is it possible to travel by overnight bus from Framingham to St Louis?

    Yes! If you're heading from Framingham to St Louis, you'll find buses departing until 2:45pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-18
US$207
05-19
No data
Today
No data
05-21
No data
05-22
No data
05-23
No data
05-24
No data
05-25
No data
busbud logoThe cheapest trip from Framingham to St Louis was searched and found on May 18, 2025 with a price of US$207

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Framingham to St Louis, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Framingham and St Louis!

Much more than a mere vehicle taking you from Framingham to St Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Framingham to St Louis will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Framingham to St Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Framingham to St Louis?

busbud logoThe bus is the cheapest travel choice for this destination

You can also go to St Louis by train

Train from Framingham to St Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

Popular Buses Connecting Framingham

Buses Leaving from Framingham

Buses Going to Framingham

Popular Buses Connecting St Louis

Buses Leaving from St Louis

Buses Going to St Louis