Find coaches from Orlando to Knoxville (TN)

Find affordable coach tickets from Orlando to Knoxville (TN) with flexible options. Book your journey now

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Today1 Jun
Tomorrow2 Jun
Tue3 Jun
from US$185
Wed4 Jun
from US$182
Thu5 Jun
from US$99
Fri6 Jun
Sat7 Jun
Sun8 Jun

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 3 June at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 3 June at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 3 June at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 4 June at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 3 June at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 4 June at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 3 June at
    Departure city: Orlando
    Departure location: The Florida Mall
    Arrival time: 4 June at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Orlando to Knoxville: Trip Overview

Average ticket priceUS$107
Average bus trip duration1d
Number of daily buses3
Earliest bus departure05:15
Distance534 miles
Latest bus departure22:40

Orlando to Knoxville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Orlando to Knoxville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Orlando to Knoxville.

Whether it is cheap bus tickets or more luxurious buses going to Knoxville from Orlando, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Orlando - Knoxville (TN)

  1. How much does a coach ticket from Orlando to Knoxville cost?

    The prices typically range from US$78 to US$319 on this trip, with the average ticket costing US$107. The actual price may differ based on factors like the time you plan to travel, the day of the week, and the coach service provider you select. Compare the prices and amenities offered by each company on Busbud and find the best deals and offers.

  2. How long does the coach from Orlando to Knoxville take?

    The coach journey between Orlando and Knoxville lasts about 1d. The quickest coach journey typically takes 15h 50m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. At what time does the first coach from Orlando to Knoxville leave?

    The first coach to Knoxville from Orlando departs at 05:15. Keep in mind that departure times might change on weekends and holidays.

  4. What's the distance between Orlando and Knoxville by coach?

    The journey from Orlando to Knoxville by coach covers an approximate distance of 534 miles (861 km).

  5. How can I travel from Orlando to Knoxville avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

  6. Can I catch a night bus from Orlando to Knoxville?

    Yes, you can find buses leaving until 22:40 and arriving the next day. Make sure to bring a snack and a blanket to keep yourself feeling comfortable during the night.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/05
No data
31/05
No data
Today
US$89
02/06
No data
03/06
US$177
04/06
US$174
05/06
No data
06/06
No data
busbud logoThe cheapest trip from Orlando to Knoxville was searched and found on 1 Jun 2025 with a price of US$89

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Knoxville as early as possible.

You can expect to pay from US$89 to US$177 for a bus ticket from Orlando to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at US$174, which is on 2025-06-04.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Orlando to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Orlando to Knoxville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Orlando to Knoxville.

Make a music playlist for your bus ride from Orlando to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Orlando by bus?

Bus from Orlando to Knoxville

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