Find coaches from San Diego (CA), US to Greenville (SC)

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Today28 May
Tomorrow29 May
from US$305
Fri30 May
Sat31 May
Sun1 Jun
Mon2 Jun
Tue3 Jun
Wed4 Jun

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 29 May at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: 1 June at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 29 May at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: 31 May at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 29 May at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: 31 May at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 29 May at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: 31 May at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 29 May at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: 1 June at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus San Diego to Greenville: Trip Overview

Average ticket priceUS$189
Average bus trip duration2d 11h
Number of daily buses9
Earliest bus departure07:15
Distance1995 miles
Latest bus departure19:35

San Diego to Greenville Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Diego to Greenville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from San Diego, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip San Diego (CA), US - Greenville (SC)

  1. How much does it cost to go to Greenville by bus?

    For coach travel from San Diego to Greenville, ticket prices typically start at US$165 and can reach a maximum of US$206. The actual price may differ based on factors like the time you plan to travel, the day of the week, and the coach service provider you select. To get accurate and up-to-date pricing information, check out all your options on our search tool.

  2. How long is a coach from San Diego to Greenville?

    The average duration for a trip from San Diego to Greenville by coach is around 2d 11h. The fastest coach journey typically takes 2d 7h. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. At what time is the first coach from San Diego to Greenville?

    The first coach to Greenville from San Diego departs at 07:15. Keep in mind that departure times might change on weekends and holidays.

  4. What's the distance between San Diego and Greenville by coach?

    The distance between San Diego and Greenville by coach is approximately 1990 miles (3210 km).

  5. What is the best way to go from San Diego to Greenville without flying?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

  6. Can I catch a night coach from San Diego to Greenville?

    Yes, you can find coaches leaving until 19:35 and arriving the next day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
26/05
No data
27/05
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Today
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29/05
US$298
30/05
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31/05
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01/06
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02/06
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busbud logoThe cheapest trip from San Diego to Greenville was searched and found on 29 May 2025 with a price of US$298

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Greenville as early as possible.

You can expect to pay from US$298 to US$298 for a bus ticket from San Diego to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at US$298, which is on 2025-05-29.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Diego to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to Greenville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to Greenville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Greenville.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to San Diego by bus?

Bus from San Diego to Greenville

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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