Bus Tickets from San Diego (CA), US to Greenville (SC)

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Bus San Diego to Greenville: Trip Overview

Average ticket price$189
Average bus trip duration2d 11h
Number of daily buses9
Earliest bus departure7:15am
Distance1995 miles (3217 km)
Latest bus departure7:35pm

San Diego to Greenville Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Diego to Greenville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from San Diego, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip San Diego (CA), US - Greenville (SC)

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/28
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05/29
$446
Today
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05/31
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06/01
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busbud logoThe cheapest trip from San Diego to Greenville was searched and found on May 29, 2025 with a price of $446

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Greenville, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Diego to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to Greenville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to Greenville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Greenville.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to San Diego by bus?

Bus from San Diego to Greenville

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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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