Find coaches from Syracuse, US to St. Louis

Next departures

Next departures from Syracuse to St. Louis on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		Syracuse (Regional Transportation Center)
    		Gateway StationCheapestFastest

    Last refresh of the prices: Yesterday at 15:01 EDT.

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    Compare 2 ways to travel from Syracuse to St. Louis

    We recommend taking the train

    Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 22 hours 2 minutes and with fares starting at just US$189, it presents an excellent value for a comfortable ride.

    1train per day
    22h 2mAverage duration
    793 milesDistance
    116kgCO₂ emissions
    Bus
    		Average priceUS$110 - US$357Average duration1d 3h
    32kg CO₂e
    Train
    		Average priceUS$189 - US$1,102Average duration22h 2m
    116kg CO₂e

    Bus Syracuse, US to St. Louis: Trip Overview

    Average ticket priceUS$165
    Average bus trip duration1d 3h
    Number of daily buses3
    Earliest bus departure04:30
    Distance793 miles
    Latest bus departure21:00

    Syracuse to St. Louis Bus

    With Busbud, comparing and booking tickets for a bus from Syracuse to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

    We make sure you can find a bus service from Syracuse to St. Louis from the most reliable bus companies operating this trip.

    Discover how much the bus trip from Syracuse to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

    Frequently asked questions on the trip Syracuse, US - St. Louis

    1. What's the distance between Syracuse and St. Louis by coach?

      The distance between Syracuse and St. Louis by coach is approximately 794 miles (1280 km).

    2. How can I travel from Syracuse to St. Louis avoiding air travel?

      You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

    Find cheapest prices for buses

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    29/10
    No data
    30/10
    US$148
    Today
    US$193
    01/11
    No data
    02/11
    No data
    03/11
    No data
    04/11
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    05/11
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    busbud logoThe cheapest trip from Syracuse, US to St. Louis was searched and found on 30 Oct 2025 with a price of US$148

    To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to St. Louis as early as possible.

    About Bus Travel

    Bus Travel Tips

    Meet and talk to locals at the bus stations while travelling from Syracuse to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

    Start sightseeing the minute your bus leaves the station. If you're on the night bus from Syracuse to St. Louis, get comfy and count the stars.

    Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Syracuse to St. Louis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

    Make a music playlist for your bus ride from Syracuse to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

    Did you know?

    One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

    Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

    Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

    What's the cheapest way to go from Syracuse, US to St. Louis?

    busbud logoThe bus is the cheapest travel choice for this destination

    Will you be returning to Syracuse, US by bus?

    Bus from St. Louis to Syracuse, US

    You can also go to St. Louis by train

    Train from Syracuse, US to St. Louis

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