Find coaches from Syracuse, US to St. Louis

Next departures

Next departures from Syracuse to St. Louis on 24 August
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Gateway StationCheapest
Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Gateway StationFastest
Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Gateway StationNo tags
Greyhound Lines, Inc.
Syracuse (Regional Transportation Center)
Gateway StationNo tags

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Compare 2 ways to travel from Syracuse to St. Louis

Bus
Average priceUS$92 - US$408Average duration1d 3h
32kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$100 - US$910Average duration22h 2m
116kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Syracuse to St. Louis

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 22 hours 2 minutes and with fares starting at just US$100, it presents an excellent value for a comfortable ride.

1train per day
22h 2mAverage duration
US$100Cheapest ticket
116kgCO₂ emissions

Bus Syracuse, US to St. Louis: Trip Overview

Average ticket priceUS$140
Average bus trip duration1d 3h
Number of daily buses2
Earliest bus departure01:45
Distance793 miles
Latest bus departure21:00

Syracuse to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Syracuse to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Syracuse to St. Louis from the most reliable bus companies operating this trip.

Discover how much the bus trip from Syracuse to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Syracuse, US - St. Louis

  1. What's the distance between Syracuse and St. Louis by coach?

    The distance between Syracuse and St. Louis by coach is approximately 794 miles (1280 km).

  2. How can I travel from Syracuse to St. Louis avoiding air travel?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
21/08
US$109
22/08
No data
Today
US$199
24/08
US$101
25/08
US$105
26/08
US$122
27/08
US$123
28/08
US$132
busbud logoThe cheapest trip from Syracuse, US to St. Louis was searched and found on 24 Aug 2025 with a price of US$101

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to St. Louis as early as possible.

You can expect to pay from US$101 to US$239 for a bus ticket from Syracuse, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$101, which is on 2025-08-24.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Syracuse to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Syracuse to St. Louis, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Syracuse to St. Louis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Syracuse to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

What's the cheapest way to go from Syracuse, US to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Syracuse, US by bus?

Bus from St. Louis to Syracuse, US

You can also go to St. Louis by train

Train from Syracuse, US to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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