How far is Syracuse from St. Louis?

About 794 miles (1280 km) separate Syracuse and St. Louis.

What are the departure and arrival stations when taking the bus from Syracuse to St. Louis?

Most of the buses traveling from Syracuse to St. Louis leave from Syracuse Airport and arrive at Gateway Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What are the best sights and things to do in St. Louis?

Once in St. Louis, you can start exploring the city and discover its surroundings. The top sights and things to do are Ulysses S. Grant National Historic Site, Scott Joplin House State Historic Site, Municipal Theatre Association, Citygarden Sculpture Park and Forest Park.

Syracuse to St. Louis from $95 | Refundable Tickets

FriAug 22

SatAug 23

SunAug 24

from $109

MonAug 25

from $112

TueAug 26

from $130

WedAug 27

ThuAug 28

FriAug 29

Cheap buses leaving Sunday

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: August 24 at 9:25am
Departure city: Syracuse
Departure location: Syracuse (Regional Transportation Center)
Arrival time: August 25 at 3:20pm
Destination city: St. Louis
Destination location: Gateway Station
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 6h
This trip is recommended because it is: Fastest
Departure time: August 24 at 4:30am
Departure city: Syracuse
Departure location: Syracuse (Regional Transportation Center)
Arrival time: August 25 at 6:25am
Destination city: St. Louis
Destination location: Gateway Station
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 2h
Departure time: August 24 at 4:30am
Departure city: Syracuse
Departure location: Syracuse (Regional Transportation Center)
Arrival time: August 25 at 6:25am
Destination city: St. Louis
Destination location: Gateway Station
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 2h
Departure time: August 24 at 9:00pm
Departure city: Syracuse
Departure location: Syracuse (Regional Transportation Center)
Arrival time: August 25 at 11:35pm
Destination city: St. Louis
Destination location: Gateway Station
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 3h

Accepted payments

Compare 2 ways to go from Syracuse to St. Louis.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$92 - $408	Average Duration1d 3h	CO₂ emissions 32kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$100 - $910	Average Duration22h 2m	CO₂ emissions 116kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the train from Syracuse to St. Louis

Among the sustainable travel choices, the train stands out as the good way to reach St. Louis. The journey takes about 22 hours 2 minutes and with fares starting at just $100, it presents an excellent value for a comfortable ride.

1train per day

22h 2mAverage Duration

$100Cheapest ticket

116kgCO₂ emissions

Bus Syracuse, US to St. Louis: Trip Overview

Average ticket price$140

Average bus trip duration1d 3h

Number of daily buses2

Earliest bus departure1:45am

Distance793 miles (1278 km)

Latest bus departure9:00pm

Compare bus companies

Greyhound

3.5/587,189 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/510,161 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Syracuse to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Syracuse to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Syracuse to St. Louis from the most reliable bus companies operating this trip.

Discover how much the bus trip from Syracuse to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Syracuse and St. Louis?

Stops in Syracuse

A - Syracuse Airport

B - Regional Transportation Center

C - Syracuse University

D - Syracuse University - Lyman Hall

E - New York State Fairgrounds

F - Syracuse, NY

Stops in St. Louis

A - Gateway Station

Frequently asked questions for your trip Syracuse, US - St. Louis

How far is Syracuse from St. Louis?
What are the departure and arrival stations when taking the bus from Syracuse to St. Louis?
What are the best sights and things to do in St. Louis?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/18

$172

08/19

$95

Today

$95

08/21

$109

08/22

No data

08/23

No data

08/24

$101

08/25

$105

The cheapest trip from Syracuse, US to St. Louis was searched and found on Aug 19, 2025 with a price of $95

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to St. Louis, as early as possible.

You can expect to pay from $95 to $196 for a bus ticket from Syracuse, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $101 which is on 2025-08-24.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Syracuse to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Syracuse to St. Louis, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Syracuse to St. Louis will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Syracuse to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

What's the cheapest way to go from Syracuse, US to St. Louis?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time1d 3h	Avg Price$140	Daily Departures2
Vehicle TypeTrain	Travel Time22h 2m	Avg Price$226	Daily Departures1

Will you be returning to Syracuse, US by bus?

Bus from St. Louis to Syracuse, US

You can also go to St. Louis by train

Train from Syracuse, US to St. Louis

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Syracuse, US to St. Louis

Cheap buses leaving Sunday

One passenger / one way

One passenger / one way

One passenger / one way

Compare 2 ways to go from Syracuse to St. Louis.

Bus Syracuse, US to St. Louis: Trip Overview

Compare bus companies

Syracuse to St. Louis Bus

Where are the popular stops in Syracuse and St. Louis?

Frequently asked questions for your trip Syracuse, US - St. Louis

How far is Syracuse from St. Louis?

What are the departure and arrival stations when taking the bus from Syracuse to St. Louis?

What are the best sights and things to do in St. Louis?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Syracuse, US to St. Louis?

Will you be returning to Syracuse, US by bus?

You can also go to St. Louis by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Syracuse

Buses Leaving from Syracuse

Buses Going to Syracuse

Popular Buses Connecting St. Louis

Buses Leaving from St. Louis

Buses Going to St. Louis

Popular routes in this country

Popular airport transfers