Bus Tickets from Appleton, WI to St Louis, MO

Find affordable bus tickets from Appleton, WI to St Louis, MO with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Bus Appleton to St Louis: Trip Overview

Average ticket price$116
Average bus trip duration13h 36m
Number of daily buses3
Earliest bus departure5:31am
Distance400 miles (645 km)
Latest bus departure10:05am

Appleton to St Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Appleton to St Louis.

We make sure you can find a bus service from Appleton to St Louis from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Appleton to St Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Appleton - St Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/02
No data
05/03
$94
Today
No data
05/05
No data
05/06
$78
05/07
No data
05/08
No data
05/09
$94
busbud logoThe cheapest trip from Appleton to St Louis was searched and found on May 6, 2025 with a price of $78

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Appleton to St Louis, as early as possible.

You can expect to pay from $78 to $318 for a bus ticket from Appleton to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $78 which is on 2025-05-06.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Appleton to St Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Appleton to St Louis, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Appleton to St Louis that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Appleton to St Louis.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Appleton by bus?

Bus from Appleton to St Louis

You can also go to St Louis by train

Train from Appleton to St Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

Popular Buses Connecting Appleton

Buses Leaving from Appleton

Buses Going to Appleton

Popular Buses Connecting St Louis

Buses Leaving from St Louis

Buses Going to St Louis