Next bus departures

Next departures for Boston to Indianapolis on September 12
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus Wifi Toilet Power outlets	12:30pm	Boston (South Station)	1d	1:15pm	Indianapolis (W Vermont St)	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	8:40pm	Brookline	21h 30m	6:10pm	Indianapolis Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	2:30am	Boston (South Station)	1d 1h	4:10am	Indianapolis Bus Station	No tags
	Bus Wifi Toilet Power outlets	8:55am	Boston (South Station)	1d	9:20am	Indianapolis Bus Station	No tags
	Bus Wifi Toilet Power outlets	2:30am	Boston (South Station)	1d	3:00am	Indianapolis (W Vermont St)	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	8:15pm	Boston (South Station)	21h 55m	6:10pm	Indianapolis Bus Station	No tags
	Bus Wifi Toilet Power outlets	9:50pm	Boston (South Station)	1d 5h	3:00am	Indianapolis (W Vermont St)	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:50pm	Boston (South Station)	1d 6h	4:10am	Indianapolis Bus Station	No tags

Last refresh of the prices: Yesterday at 7:01 PM EDT.

Compare 2 ways to go from Boston to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Indianapolis. The journey takes about 1 day, 1 hour 30 minutes and with fares starting at just COP 323,984, it presents an excellent value for a comfortable ride.

16bus per day

1d 1hAverage Duration

803 milesDistance

32kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCOP 323,984 - COP 1,224,349	Average Duration1d 1h	CO₂ emissions 32kg CO₂e
Train	Average PriceCOP 429,418 - COP 3,886,560	Average Duration1d 10h	CO₂ emissions 118kg CO₂e

Bus stations and stops in Boston and Indianapolis

Stops in Boston

A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA
Visit page
B
North Station
100 Legends Way, Boston, MA 02114, USA
Visit page
C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA
D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA
E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA
F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Compare bus companies

FlixBus

3.5/515,614 reviews

Staff4.1

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/588,135 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies:FlixBus, Greyhound, Futura, Chihuahuenses, Tufesa, Adirondack Trailways, Valley Transit

Frequently asked questions about traveling from Boston, MA, US to Indianapolis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Boston to Indianapolis?
The cheapest bus tickets from Boston to Indianapolis start from COP 323,984. The average price for this route is around COP 558,215. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Boston to Indianapolis?
The average bus trip duration from Boston to Indianapolis is 1d 1h, covering a distance of 803 miles (1295 km). The quickest bus can get you there in 1d and is operated by Greyhound.
Which bus companies service the Boston to Indianapolis route?
Several major bus companies operate on this route with 16 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Boston to Indianapolis?
The earliest bus departs from Boston to Indianapolis at 1:30am. And the latest bus departs at 9:50pm.
What are the CO₂ emissions for the bus trip from Boston to Indianapolis?
A bus trip from Boston to Indianapolis generates an estimated 32.35675 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Boston to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 15443 reviews.
Which bus company has the best Wi-Fi from Boston to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Boston to Indianapolis?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Boston to Indianapolis?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/09

COP 567,235

09/10

COP 567,235

Today

COP 541,737

09/12

COP 557,705

09/13

COP 544,924

09/14

COP 452,526

09/15

COP 313,849

09/16

COP 301,131

The cheapest trip from Boston, MA, US to Indianapolis was searched and found on Sep 16, 2026 with a price of COP 301,131

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Indianapolis, as early as possible.

You can expect to pay from COP 301,131 to COP 771,250 for a bus ticket from Boston, MA, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at COP 301,131 which is on 2026-09-16.

Usually FlixBus, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.