Bus Tickets from Boston, MA, US to Indianapolis

Next bus departures

Next departures for Boston to Indianapolis on November 23
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
Boston (South Station)
Downtown Transit CenterCheapest
Greyhound Lines, Inc.Bus
Boston (South Station)
Indianapolis Bus StationFastest
Greyhound Lines, Inc.Bus
Boston (South Station)
Indianapolis Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
Indianapolis Bus StationNo tags
FlixBusBus
Brookline
Downtown Transit CenterNo tags

Last refresh of the prices: Last Sunday at 2:13 PM EST.

Compare 2 ways to go from Boston to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 1 day, 4 hours 25 minutes and with fares starting at just $103, it presents an excellent value for a comfortable ride.

18bus per day
1d 4hAverage Duration
801 milesDistance
32kgCO₂ emissions
Average Price$103 - $432Average Duration1d 4h
32kg CO₂e
Average Price$128 - $484Average Duration1d 10h
118kg CO₂e

Frequently asked questions about traveling from Boston, MA, US to Indianapolis by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/19
$188
11/20
$224
Today
$248
11/22
$239
11/23
$200
11/24
No data
11/25
$207
11/26
$235
busbud logoThe cheapest trip from Boston, MA, US to Indianapolis was searched and found on Nov 19, 2025 with a price of $188

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Indianapolis, as early as possible.

You can expect to pay from $188 to $371 for a bus ticket from Boston, MA, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $200 which is on 2025-11-23.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Boston, MA, US to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

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