Bus from Chicago to San Antonio, US: Tickets & Schedules
Next bus departures
Next departures for Chicago to San Antonio on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Chicago 95Th & Dan Ryan
Pearl District
Cheapest
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Downtown Greyhound Station
Pearl District
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
537-517 W. Jackson Blvd
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
No tags
Next departures for Chicago to San Antonio on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Pearl District
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Pearl District
No tags
Next departures for Chicago to San Antonio on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Pearl District
No tags
Next departures for Chicago to San Antonio on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Chicago, IL
Tornado I-35
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Pearl District
No tags
Next departures for Chicago to San Antonio on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Pearl District
No tags
Next departures for Chicago to San Antonio on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Pearl District
No tags
Next departures for Chicago to San Antonio on December 2
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
No tags
Next departures for Chicago to San Antonio on December 3
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Pearl District
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Downtown Greyhound Station
Pearl District
No tags
Last refresh of the prices: Yesterday at 9:08 PM CST.
Compare 2 ways to go from Chicago to San Antonio
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach San Antonio. The journey takes about 1 day, 3 hours 10 minutes and with fares starting at just $102, it presents an excellent value for a comfortable ride.
A Texas-based company, Tornado Bus operates throughout the United States, with routes connecting major cities, including Houston, San Antonio and El Paso. Each day,10 buses leave from their terminals to destinations across the continent. Their buses are equipped with free Wi-Fi, air conditioning, bathrooms, power outlets and a comfortable amount of legroom. With prices as low as $258 for a short ride, Tornado offers options for budget travelers, without compromising comfort. and those looking for a little luxury. The company requires printed tickets for boarding and their tickets are non-refundable, but you can exchange them up to two hours before travel time for a fee. With a friendly staff and multiple routes, traveling with Tornado is a convenient way to get around.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Chicago to San Antonio, US by bus
What is the distance between Chicago and San Antonio?
The distance separating Chicago and San Antonio is 1050 miles (1693 km).
What are the departure and arrival stations when taking the bus from Chicago to San Antonio?
If you're headed to San Antonio from Chicago, chances are that your bus will leave from Downtown Greyhound Station and arrive at Tornado I-35. These are the most popular pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in San Antonio?
Once in San Antonio, you can start exploring the city and discover its surroundings. The top sights and things to do are River Walk, Traders Village, The Alamo, San Antonio Zoo and SeaWorld San Antonio.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
$275
11/25
$275
Today
$275
11/27
$275
11/28
$275
11/29
$275
11/30
$275
12/01
$275
The cheapest trip from Chicago to San Antonio, US was searched and found on Nov 24, 2025 with a price of $275
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to San Antonio, US, as early as possible.
You can expect to pay from $275 to $290 for a bus ticket from Chicago to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at $275 which is on 2025-11-27.
The cheapest trip from Chicago to San Antonio, US was searched and found on Nov 24, 2025 with a price of $275
