Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Columbus (E Mound St) | Syracuse (Regional Transportation Center) | Cheapest | ||||
| Bus | Columbus (E Mound St) | Syracuse (Regional Transportation Center) | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 100 E Rich St | Syracuse (Regional Transportation Center) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Columbus (E Mound St) | Syracuse (Regional Transportation Center) | No tags |
Last refresh of the prices: Last Thursday at 5:22 PM EDT.
Get from Columbus to Syracuse
The journey takes about 18 hours 5 minutes and with fares starting at just $138, it presents an excellent value for a comfortable ride.
Where are the popular stops in Columbus and Syracuse?
Stops in Columbus
- A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
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Frequently asked questions about traveling from Columbus, OH to Syracuse, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Columbus to Syracuse?
The cheapest bus tickets from Columbus to Syracuse start from $138. The average price for this route is around $141. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Columbus to Syracuse?
The average bus trip duration from Columbus to Syracuse is 18h 5m, covering a distance of 413 miles (666 km). The quickest bus can get you there in 12h 35m and is operated by Greyhound.
Which bus companies service the Columbus to Syracuse route?
What is the earliest and latest departure time for the bus from Columbus to Syracuse?
The earliest bus departs from Columbus to Syracuse at 3:45am. And the latest bus departs at 9:10pm.
What are the CO₂ emissions for the bus trip from Columbus to Syracuse?
A bus trip from Columbus to Syracuse generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Columbus to Syracuse?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87527 reviews.
Which bus company has the best Wi-Fi from Columbus to Syracuse?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Columbus to Syracuse?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Columbus to Syracuse?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Columbus, OH to Syracuse, US was searched and found on Mar 16, 2026 with a price of $86To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus, OH to Syracuse, US, as early as possible.
You can expect to pay from $86 to $172 for a bus ticket from Columbus, OH to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $86 which is on 2026-03-16.
