Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Columbus (E Mound St) | Syracuse (Regional Transportation Center) | CheapestFastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 100 E Rich St | Syracuse (Regional Transportation Center) | No tags | ||||
| Bus | Columbus (E Mound St) | Syracuse (Regional Transportation Center) | No tags |
Last refresh of the prices: Yesterday at 1:30 AM EDT.
Get from Columbus to Syracuse
The journey takes about 14 hours 10 minutes and with fares starting at just $70, it presents an excellent value for a comfortable ride.
Where are the popular stops in Columbus and Syracuse?
Stops in Columbus
- A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Columbus Syracuse recent customer reviews
Continue the spirit
Jean N.
great station with good people
Jit N.
Frequently asked questions about traveling from Columbus, OH to Syracuse, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Columbus to Syracuse?
The cheapest bus tickets from Columbus to Syracuse start from $70. The average price for this route is around $82. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Columbus to Syracuse?
The average bus trip duration from Columbus to Syracuse is 14h 10m, covering a distance of 413 miles (666 km). The quickest bus can get you there in 12h 35m and is operated by Greyhound.
Which bus companies service the Columbus to Syracuse route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Columbus to Syracuse?
The earliest bus departs from Columbus to Syracuse at 3:45am. And the latest bus departs at 9:10pm.
What are the CO₂ emissions for the bus trip from Columbus to Syracuse?
A bus trip from Columbus to Syracuse generates an estimated 16.636275 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Columbus, OH to Syracuse, US was searched and found on Jun 5, 2026 with a price of $68To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus, OH to Syracuse, US, as early as possible.
You can expect to pay from $68 to $138 for a bus ticket from Columbus, OH to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $68 which is on 2026-06-05.
