Next departures for Eugene to San Diego on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Eugene (U of O - Jaqua Academic Ctr)
UCSD Health La Jolla Station
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Eugene (U of O - Jaqua Academic Ctr)
Greyhound Bus Stop
Fastest
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Eugene (U of O - Jaqua Academic Ctr)
San Diego (Old Town-FlixBus)
No tags
FlixBus + Greyhound Lines, Inc. + FlixBus
Bus
Eugene (U of O - Jaqua Academic Ctr)
Downtown SD (Seaport)
No tags
Last refresh of the prices: Yesterday at 6:40 PM PST.
Compare 2 ways to go from Eugene to San Diego
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 1 day, 7 hours 49 minutes and with fares starting at just $160, it presents an excellent value for a comfortable ride.
Based on 5597 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $236
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Eugene to San Diego, CA, US by bus
What is the travel distance from Eugene to San Diego?
Eugene and San Diego are 846 miles (1364 km) apart.
What are the departure and arrival stations when taking the bus from Eugene to San Diego?
The majority of buses traveling from Eugene to San Diego start their journey at University of Oregon - Hayward Field and wind up at Mission Valley Sheraton. These are the most popular departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in San Diego?
Once in San Diego, you can start exploring the city and discover its surroundings. The top sights and things to do are Cabrillo National Monument, Pacific Surf School, Coronado, SeaWorld San Diego and Old Town.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$274
11/20
$368
Today
$368
11/22
No data
11/23
$254
11/24
$254
11/25
$313
11/26
$293
The cheapest trip from Eugene to San Diego, CA, US was searched and found on Nov 23, 2025 with a price of $254
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Eugene to San Diego, CA, US, as early as possible.
You can expect to pay from $254 to $721 for a bus ticket from Eugene to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $254 which is on 2025-11-23.
What's the cheapest way to go from Eugene to San Diego, CA, US?
The bus is the cheapest travel choice for this destination