Bus Mexico City to Santiago: Trip Overview
Mexico to Santiago Buses
Busbud helps you find a bus from Mexico to Santiago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Mexico to Santiago from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Mexico to Santiago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular bus stations and stops in Mexico and Santiago?
Terminal del Sur, Av. Taxqueña No. 1320 (Col. Campestre Churubusco), 04200 Coyoacán - Ciudad de Mexico
SurTerminal del Norte, Eje Central 271, Magdalena de las Salinas, 07760 Ciudad de México, D.F., Mexico
NorteCalle Economía, Aeropuerto Int de La Cd de México, 15620 Ciudad de México, CDMX, Mexico
Aeropuerto MEX T2Calz. Ignacio Zaragoza 564d, 4 Árboles, 15730 Ciudad de México, CDMX, Mexico
ZaragozaCalle Sur 122 No. 232 (Esq. Con Avenida Río Tacubaya, estación metro Observatorio) - Real del Monte, Alvaro Obregon, 11300 Ciudad de México
PonienteFrequently asked questions for your trip Mexico City - Santiago
The best way to travel from Mexico City to Santiago is by bus. Traveling by bus offers a budget-friendly, secure, and easy way to go between the two cities. Alternatively, you can also use carpooling services.
The average travel time from Mexico City to Santiago is about 10h 30m, but you can get there in as little as 10h 30m with the quickest bus. This is the time it takes to travel the 419 miles (676 km) that separate the two cities.
The distance between the two cities is 419 miles (676 km).
The majority of buses traveling from Mexico City to Santiago start their journey at Sur and wind up at EL RANCHITO, NL. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
The cheapest way to travel this route is by bus. The lowest price for the bus on this route is $95.
The average bus ticket price from Mexico City to Santiago is $95. Over the last 30 days, the prices ranged between $95 and $95, so make sure to compare them to get the best option.
Yes, it is possible to take an overnight bus from Mexico City to Santiago. Don't forget to bring a snack and a blanket to help you stay comfortable through the night.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mexico City and Santiago!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Mexico City to Santiago, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Mexico City to Santiago that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Mexico City to Santiago while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Will you be returning to Mexico City by bus?
Bus from Santiago to Mexico CityWhy choose Busbud?
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
Popular Buses Connecting Mexico City
Buses Leaving from Mexico City
- Bus from Mexico to Acapulco
- Bus Mexico - Tijuana
- Mexico - Santa Ana
- Bus from Mexico to Tulum
- Bus Mexico - San Miguel de Allende
- Mexico - Ciudad Juarez
- Bus from Mexico to Puerto Escondido
- Bus Mexico - Santiago de Querétaro
- Mexico - Cancún
- Bus from Mexico to Puerto Vallarta
- Bus Mexico - Cuernavaca
- Mexico - Monterrey
- Bus from Mexico to Taxco
- Bus Mexico - Veracruz
- Mexico - Tepoztlán
Buses Going to Mexico City
- Bus from Salina Cruz to Mexico
- Bus San Luis Potosí - Mexico
- Tapachula - Mexico
- Bus from Tecuala to Mexico
- Bus Pachuca - Mexico
- Zapopan - Mexico
- Bus from Cancún to Mexico
- Bus Guadalajara - Mexico
- Puerto Escondido - Mexico
- Bus from Tijuana to Mexico
- Bus Puerto Vallarta - Mexico
- Monterrey - Mexico
- Bus from Santiago de Querétaro to Mexico
- Bus Chetumal - Mexico
- Acapulco - Mexico
Popular Buses Connecting Santiago
Buses Leaving from Santiago
- Bus from Santiago to Jiménez
- Bus Santiago - Zaragoza
- Santiago - Laredo
- Bus from Santiago to San Pedro
- Bus Santiago - Reynosa
- Santiago - Montemorelos
- Bus from Santiago to Mexico
- Bus Santiago - Mazatlán
- Santiago - Monterrey
- Bus from Santiago to Guadalupe
- Bus Santiago - Matamoros
- Santiago - San Marcos
- Bus from Santiago to Tepic
- Bus Santiago - Esperanza
- Santiago - Juárez
Buses Going to Santiago
- Bus from Matamoros to Santiago
- Bus Corona - Santiago
- Esperanza - Santiago
- Bus from Guadalupe to Santiago
- Bus San Marcos - Santiago
- Juárez - Santiago
- Bus from Monterrey to Santiago
- Bus Mexico - Santiago
- Montemorelos - Santiago
- Bus from Reynosa to Santiago
- Bus Zaragoza - Santiago
- San Pedro - Santiago
- Bus from Mazatlán to Santiago
- Bus Tepic - Santiago
- Bustamante - Santiago
Popular routes in this country
- Bus from Cancún to Chiquilá
- Bus Puerto Escondido - Oaxaca
- Chetumal - Cancún
- Bus from Tulum to Bacalar
- Bus Tulum - Playa del Carmen
- Chiquilá - Cancún
- Bus from Cancún to Valladolid
- Bus Puebla - Oaxaca
- Cancún - Bacalar
- Bus from Oaxaca to San Cristóbal de las Casas
- Bus Cancún - Chichén-Itzá
- Bacalar - Cancún
- Bus from Puebla to Mexico
- Bus Bacalar - Tulum
- Puerto Escondido - San Cristóbal de las Casas