Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Jet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United StatesJet Set Express Terminal
D - Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830
E - International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA
F - Seaworld Hotels
10100 International Drive , Orlando, 32821
Frequently asked questions about traveling from Port Saint Lucie to Orlando by bus
What is the travel distance from Port Saint Lucie to Orlando?
The distance between the two cities is 107 miles (172 km).
What are the departure and arrival stations when taking the bus from Port Saint Lucie to Orlando?
The majority of buses traveling from Port Saint Lucie to Orlando start their journey at Port St Lucie Mobil Gas Bus Stop and wind up at Orlando Bus Station. These are the primary departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Orlando?
Once in Orlando, you can start exploring the city and discover its surroundings. The top sights and things to do are Harry P. Leu Gardens, K1 Speed, ESPN Wide World of Sports Complex, Orlando Science Center and Dr. Phillips Cinedome and Orlando Shakespeare Theater.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$63
11/18
$33
Today
$47
11/20
$32
11/21
$33
11/22
$33
11/23
$36
11/24
$37
The cheapest trip from Port Saint Lucie to Orlando was searched and found on Nov 20, 2025 with a price of $32
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Port Saint Lucie to Orlando, as early as possible.
You can expect to pay from $32 to $63 for a bus ticket from Port Saint Lucie to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $32 which is on 2025-11-20.