Bus Tickets from San Antonio, TX to San Diego, CA

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TodayMay 13
from $291
TomorrowMay 14
from $231
ThuMay 15
FriMay 16
SatMay 17
SunMay 18
MonMay 19
TueMay 20

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 14 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 15 at
    Destination city: San Diego
    Destination location: Downtown SD (Seaport)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 14 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 15 at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 15 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 16 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: Valley Transit Co., Inc. + Greyhound Lines, Inc. + FlixBus
    Valley Transit Co., Inc. + Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: May 15 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines Mexico + Greyhound Lines, Inc.
    Greyhound Lines Mexico + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from San Antonio to San Diego.

Bus
Average Price$85 - $481Average Duration1d 17h
45kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$159 - $353Average Duration1d 9h
165kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from San Antonio to San Diego

Among the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 1 day, 9 hours 5 minutes and with fares starting at just $159, it presents an excellent value for a comfortable ride.

2train per day
1d 9hAverage Duration
$159Cheapest ticket
165kgCO₂ emissions

Bus San Antonio to San Diego: Trip Overview

Average ticket price$152
Average bus trip duration1d 17h
Number of daily buses12
Earliest bus departure1:30am
Distance1125 miles (1814 km)
Latest bus departure9:45pm

San Antonio to San Diego Bus

With Busbud, comparing and booking tickets for a bus from San Antonio to San Diego is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from San Antonio to San Diego will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from San Antonio to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip San Antonio - San Diego

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/11
No data
05/12
No data
Today
No data
05/14
No data
05/15
$102
05/16
$141
05/17
$96
05/18
$102
busbud logoThe cheapest trip from San Antonio to San Diego was searched and found on May 17, 2025 with a price of $96

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio to San Diego, as early as possible.

You can expect to pay from $96 to $141 for a bus ticket from San Antonio to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at $96 which is on 2025-05-17.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Antonio to San Diego.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from San Antonio to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Antonio to San Diego that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from San Antonio to San Diego while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from San Antonio to San Diego?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Antonio by bus?

Bus from San Antonio to San Diego

You can also go to San Diego by train

Train from San Antonio to San Diego

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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