Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Springfield Flixbus stop | Greyhound Bus Stop | No tags | ||||
Greyhound + FlixBus | Bus | Springfield Flixbus stop | Balboa Park | No tags | ||||
FlixBus + Greyhound | Bus | Springfield Flixbus stop | San Diego (Old Town-FlixBus) | No tags | ||||
FlixBus + Greyhound | Bus | Springfield Flixbus stop | UCSD Health La Jolla Station | No tags | ||||
Greyhound + FlixBus | Bus | Springfield Flixbus stop | Downtown SD (Seaport) | No tags |
Get from Springfield to San Diego
The journey takes about 1 day, 18 hours 55 minutes and with fares starting at just $316, it presents an excellent value for a comfortable ride.
Where are the popular stops in Springfield and San Diego?
Stops in Springfield
- A
Greyhound Station
2425 E Kearney St, Springfield, MO 65803 - B
I-44 & Kansas Expy
2825 N Kansas Expy, Springfield, MO 65806, USA
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Springfield, MO to San Diego, CA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Springfield to San Diego?
The cheapest bus tickets from Springfield to San Diego start from $316. The average price for this route is around $387. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Springfield to San Diego?
The average bus trip duration from Springfield to San Diego is 1d 18h, covering a distance of 1381 miles (2227 km). The quickest bus can get you there in 1d 20h and is operated by Greyhound.
Which bus companies service the Springfield to San Diego route?
Several major train operators operate on this route with 3 trains available per day.
What is the earliest and latest departure time for the bus from Springfield to San Diego?
The earliest bus departs from Springfield to San Diego at 3:20am. And the latest bus departs at 5:20am.
What are the CO₂ emissions for the bus trip from Springfield to San Diego?
A bus trip from Springfield to San Diego generates an estimated 56 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Springfield, MO to San Diego, CA, US was searched and found on Dec 31, 2025 with a price of $348To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Springfield, MO to San Diego, CA, US, as early as possible.
Top traveled bus routes
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