Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Syracuse (Regional Transportation Center) | Portland Curbside Bus Stop | CheapestFastest |
Last refresh of the prices: Last Saturday at 10:41 PM EST.
Compare 2 ways to go from Syracuse to Portland
Among the sustainable travel choices, the bus stands out as the good way to reach Portland. The journey takes about 4 days, 3 hours 45 minutes and with fares starting at just $227, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Portland?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Portland
- B7411 Northwest Station Way, Portland OR 97209, USA
- C
NW Everett & NW 8th Ave
728 NW Everett St, Portland, OR 97209, USA - D
Lloyd Center
NE 13th Ave & Holladay, Portland, OR 97232, USA - E
Pearl District
7418 NW Station Way (across street), Portland, OR 97209, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Syracuse, US to Portland, OR by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to Portland?
The cheapest bus tickets from Syracuse to Portland start from $227. The average price for this route is around $288. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Portland?
The average bus trip duration from Syracuse to Portland is 4d 3h, covering a distance of 2269 miles (3660 km). The quickest bus can get you there in 3d 15h and is operated by Greyhound.
Which bus companies service the Syracuse to Portland route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Syracuse to Portland?
The earliest bus departs from Syracuse to Portland at 3:00am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Portland?
A bus trip from Syracuse to Portland generates an estimated 91 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Portland, OR was searched and found on Dec 16, 2025 with a price of $219To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Portland, OR, as early as possible.
You can expect to pay from $219 to $452 for a bus ticket from Syracuse, US to Portland, OR based on the last 2 days. You can expect to find the cheapest price for the trip at $219 which is on 2025-12-16.
What's the cheapest way to go from Syracuse, US to Portland, OR?
The bus is the cheapest travel choice for this destination
