Next departures to St. Louis
One passenger / one way
- This trip is recommended because it is: Cheapest
- This trip is recommended because it is: Fastest
- Departure time: July 25 atDeparture city: TampaDeparture location: Union StationArrival time: July 27 atDestination city: St. LouisDestination location: Gateway StationOperated by: Amtrak
Vehicle: BusDuration: - Departure time: July 25 atDeparture city: TampaDeparture location: Tampa Bus StationArrival time: July 26 atDestination city: St. LouisDestination location: Gateway StationOperated by: FlixBus
Vehicle: BusDuration:
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Compare 2 ways to go from Tampa to St. Louis.
Busbud recommends taking the bus from Tampa to St. LouisAmong the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 1 day, 1 hour 40 minutes and with fares starting at just $97, it presents an excellent value for a comfortable ride.
Bus Tampa to St. Louis: Trip Overview
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Tampa to St. Louis Bus
Busbud helps you find a bus from Tampa to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Tampa to St. Louis from the most reliable bus companies operating this trip.
Discover how much the bus trip from Tampa to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Tampa and St. Louis?
Frequently asked questions for your trip Tampa - St. Louis
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tampa to St. Louis was searched and found on Jul 28, 2025 with a price of $111To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to St. Louis, as early as possible.
You can expect to pay from $111 to $2,928 for a bus ticket from Tampa to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $111 which is on 2025-07-28.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tampa and St. Louis!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Tampa to St. Louis, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Tampa to St. Louis will emit less CO2 than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from Tampa to St. Louis while indulging in miles on end of beautiful scenic views.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
What's the cheapest way to go from Tampa to St. Louis?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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