Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Ft Myers Bus Station | Port St. Lucie (Park & Ride) | CheapestFastest |
Last refresh of the prices: Today at 1:20 PM EST.
Get from Fort Myers to Port Saint Lucie
The journey takes about 7 hours 5 minutes, and with fares starting at just $49, it presents an excellent value for a comfortable ride.
Where are the popular stops in Fort Myers and Port Saint Lucie?
Stops in Fort Myers
- A
Daniels Pkwy & I-75
13600 Indian Paint Ln (McDonald's on Daniels Pwy and I-75), Fort Myers, FL 33912 - B
Colonial Blvd & I-75
Walmart, 4770 Colonial Blvd, Fort Myers, FL 33966 - C
Rosa Parks
2250 Widman Way, Fort Myers, FL 33901
Stops in Port Saint Lucie
- A
Port St Lucie Mobil Gas Bus Stop
1820 Sw Fountainview Blvd, Port Saint Lucie, FL 34986 - B
Port Saint Lucie - Wendys
1790 SW St Lucie W Blvd, Port St Lucie, FL 34986 - C
Port Saint LucieService Plaza
Florida's Turnpike, Milepost 144, Port St Lucie, FL 34984, USA - D
Port Saint Lucie Bus Stop
2198 SW Gatlin Blvd. Port St. Lucie, FL 34953
Compare bus companies
Based on 11473 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $49
Frequently asked questions about travelling from Fort Myers to Port Saint Lucie by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Fort Myers to Port Saint Lucie?
The cheapest bus tickets from Fort Myers to Port Saint Lucie start from $49. The average price for this route is around $86. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Fort Myers to Port Saint Lucie?
The average bus travel time from Fort Myers to Port Saint Lucie is 7h 5m, covering a distance of 160 km. The quickest bus can get you there in 7h 5m and is operated by FlixBus.
Which bus companies service the Fort Myers to Port Saint Lucie route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Fort Myers to Port Saint Lucie?
The earliest bus departs from Fort Myers to Port Saint Lucie at 6:30pm. And the latest bus departs at 6:30pm.
What are the CO₂ emissions for the bus trip from Fort Myers to Port Saint Lucie?
A bus trip from Fort Myers to Port Saint Lucie generates an estimated 4 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Fort Myers to Port Saint Lucie was searched and found on Nov 27, 2025 with a price of $86To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Fort Myers to Port Saint Lucie, as early as possible.
You can expect to pay from $86 to $148 for a bus ticket from Fort Myers to Port Saint Lucie based on the last 2 days. You can expect to find the cheapest price for the trip at $91 which is on 2025-12-01.
