Next departures to Florence
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: FastestDeparture time: June 29 atDeparture city: TampaDeparture location: Union StationArrival time: June 29 atDestination city: FlorenceDestination location: Florence StationOperated by: Amtrak
Vehicle: BusDuration: - Departure time: June 29 atDeparture city: TampaDeparture location: Union StationArrival time: June 29 atDestination city: FlorenceDestination location: Florence StationOperated by: AmtrakVehicle: BusDuration:
- Departure time: June 29 atDeparture city: TampaDeparture location: Tampa Bus StationArrival time: June 30 atDestination city: FlorenceDestination location: Bus stationOperated by: FlixBus
Vehicle: BusDuration:
Last refresh of the prices: Yesterday at 12:01 PM EDT.
Prices and availability are subject to change.
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Compare 2 ways to go from Tampa to Florence
Busbud recommends taking the train from Tampa to FlorenceAmong the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 18 hours 4 minutes, and with fares starting at just US$93, it presents an excellent value for a comfortable ride.
Bus Tampa to Florence: Trip Overview
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Tampa to Florence Bus
Busbud helps you find a bus from Tampa to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Tampa to Florence.
Whether it is cheap bus tickets or more luxurious buses going to Florence from Tampa, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Tampa and Florence?
Frequently asked questions on the trip Tampa - Florence, SC, US
What is the travel distance from Tampa to Florence?
The distance between Tampa and Florence is approximately 747 km (464 miles).
What are the departure and arrival locations for buses traveling from Tampa to Florence?
Buses departing from Tampa 13th Avenue Bus Stop (McDonald's) in Tampa will take you to Florence Bus Station in Florence.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tampa to Florence was searched and found on Jun 22, 2025 with a price of US$49To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Florence, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tampa and Florence!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Tampa to Florence.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tampa to Florence.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tampa to Florence.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
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Popular Buses Connecting Florence
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Buses Going to Florence
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