How can I travel from Tampa to Florence without flying?

Both buses and trains are available for traveling between these two cities. Either way you choose, you'll be sure to reach your destination in the most practical and sustainable way. Another option you should consider is using carpooling services, which allow you to share a car ride with other travelers.

How long does it take to get to Florence from Tampa by bus?

Traveling from Tampa to Florence takes around 1d 1h on average, although the minimum time it takes to get there is 14h 29m with the fastest bus. This is the time it takes to travel the 464 miles (747 km) that separate the two cities.

What is the travel distance from Tampa to Florence?

Tampa and Florence are 464 miles (747 km) apart.

What are the departure and arrival stations when taking the bus from Tampa to Florence?

The majority of buses traveling from Tampa to Florence start their journey at Tampa 13th Avenue Bus Stop (McDonald's) and wind up at Florence Bus Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What is the most affordable way to go from Tampa to Florence?

You can save a lot of money on your trip from Tampa to Florence by choosing to travel by bus. The lowest price for the bus on this route is $73.

How much are the bus tickets from Tampa to Florence?

The bus ticket costs $88 on average. Over the last 30 days, the prices ranged between $73 and $149, so make sure to compare them to get the best option.

What are the best sights and things to do in Florence?

Once in Florence, you can start exploring the city and discover its surroundings. The top sights and things to do are Palazzo Vecchio, Santa Maria Novella, Basilica di San Lorenzo, Leonardo Da Vinci Museum and Tuscan Wine Tour.

Tampa to Florence (SC), US Bus Tickets

TodayMay 3

TomorrowMay 4

MonMay 5

TueMay 6

WedMay 7

from $136

ThuMay 8

from $112

FriMay 9

from $166

SatMay 10

Next departures to Florence

One passenger / one way

This trip is recommended because it is: Cheapest + Fastest
Departure time: May 7 at 10:25am
Departure city: Tampa
Departure location: Union Station
Arrival time: May 7 at 11:22pm
Destination city: Florence
Destination location: Florence Station
Operated by: Amtrak
Vehicle: BusDuration: 12h 57m
Departure time: May 7 at 10:25am
Departure city: Tampa
Departure location: Union Station
Arrival time: May 7 at 11:22pm
Destination city: Florence
Destination location: Florence Station
Operated by: Amtrak
Vehicle: BusDuration: 12h 57m

Accepted payments

Compare 2 ways to go from Tampa to Florence.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$73 - $149	Average Duration1d 1h	CO₂ emissions 18kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$93 - $93	Average Duration18h 4m	CO₂ emissions 67kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the train from Tampa to Florence

Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 18 hours 4 minutes and with fares starting at just $93, it presents an excellent value for a comfortable ride.

1train per day

18h 4mAverage Duration

$93Cheapest ticket

67kgCO₂ emissions

Bus Tampa to Florence: Trip Overview

Average ticket price$88

Average bus trip duration1d 1h

Number of daily buses2

Earliest bus departure9:30am

Distance451 miles (727 km)

Latest bus departure10:35pm

Compare bus companies

FlixBus

3.5/58,487 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.6

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/586,956 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Amtrak

4/55,092 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

US bus companies: FlixBus, Greyhound, Los Limousines, Tornado Bus, Valley Transit, New York Trailways, Wanda Coach

Tampa to Florence Bus

Busbud helps you find a bus from Tampa to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Tampa to Florence.

Whether it is cheap bus tickets or more luxurious buses going to Florence from Tampa, we help you find what you're looking for based on how much of a budget you have.

Where are the popular stops in Tampa and Florence?

Stops in Tampa

A - Tampa 13th Avenue Bus Stop (McDonald's)

B - Tampa USF, FL

C - Greyhound Station

D - E Sligh Ave

E - N Marion St & E Laurel St

F - Port of Tampa

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Frequently asked questions for your trip Tampa - Florence

How can I travel from Tampa to Florence without flying?
How long does it take to get to Florence from Tampa by bus?
What is the travel distance from Tampa to Florence?
What are the departure and arrival stations when taking the bus from Tampa to Florence?
What is the most affordable way to go from Tampa to Florence?
How much are the bus tickets from Tampa to Florence?
What are the best sights and things to do in Florence?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/01

$90

05/02

$112

Today

$92

05/04

No data

05/05

No data

05/06

No data

05/07

$136

05/08

$112

The cheapest trip from Tampa to Florence was searched and found on May 1, 2025 with a price of $90

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Florence, as early as possible.

You can expect to pay from $90 to $515 for a bus ticket from Tampa to Florence based on the last 2 days. You can expect to find the cheapest price for the trip at $112 which is on 2025-05-08.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tampa and Florence!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Tampa to Florence.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tampa to Florence.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tampa to Florence.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Tampa to Florence?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time1d 1h	Avg Price$88	Daily Departures2
Vehicle TypeTrain	Travel Time18h 4m	Avg Price$93	Daily Departures1

Will you be returning to Tampa by bus?

Bus from Tampa to Florence

You can also go to Florence by train

Train from Tampa to Florence

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Tampa, FL to Florence, SC

Next departures to Florence

One passenger / one way

One passenger / one way

One passenger / one way

Compare 2 ways to go from Tampa to Florence.

Bus Tampa to Florence: Trip Overview

Compare bus companies

Tampa to Florence Bus

Where are the popular stops in Tampa and Florence?

Frequently asked questions for your trip Tampa - Florence

How can I travel from Tampa to Florence without flying?

How long does it take to get to Florence from Tampa by bus?

What is the travel distance from Tampa to Florence?

What are the departure and arrival stations when taking the bus from Tampa to Florence?

What is the most affordable way to go from Tampa to Florence?

How much are the bus tickets from Tampa to Florence?

What are the best sights and things to do in Florence?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Tampa to Florence?

Will you be returning to Tampa by bus?

You can also go to Florence by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Tampa

Buses Leaving from Tampa

Buses Going to Tampa

Popular Buses Connecting Florence

Buses Leaving from Florence

Buses Going to Florence

Popular routes in this country

Popular airport transfers