Find coaches from St. Louis to Spartanburg

Next departures

Next departures from St. Louis to Spartanburg on 4 September
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Gateway Station
SpartanburgCheapest
FlixBus + Greyhound Lines, Inc.
Gateway Station
SpartanburgFastest
FlixBus + Greyhound Lines, Inc.
Gateway Station
SpartanburgNo tags
Greyhound Lines, Inc. + FlixBus
Gateway Station
SpartanburgNo tags
FlixBus + Greyhound Lines, Inc.
Gateway Station
SpartanburgNo tags

Accepted payments

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Compare 2 ways to travel from St. Louis to Spartanburg

Bus
Average priceUS$111 - US$183Average duration20h 25m
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$573 - US$1,604Average duration1d 19h
77kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St. Louis to Spartanburg

Among the sustainable travel choices, the bus stands out as a good way to reach Spartanburg. The journey takes about 20 hours 25 minutes and with fares starting at just US$111, it presents an excellent value for a comfortable ride.

3bus per day
20h 25mAverage duration
US$111Cheapest ticket
21kgCO₂ emissions

Bus St. Louis to Spartanburg: Trip Overview

Average ticket priceUS$157
Average bus trip duration20h 25m
Number of daily buses3
Earliest bus departure02:35
Distance517 miles
Latest bus departure23:30

St. Louis to Spartanburg Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from St. Louis to Spartanburg.

Bus service from St. Louis to Spartanburg will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from St. Louis to Spartanburg, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip St. Louis - Spartanburg

  1. What's the distance between St. Louis and Spartanburg by coach?

    The distance between St. Louis and Spartanburg by coach is approximately 523 miles (843 km).

  2. How can I travel from St. Louis to Spartanburg avoiding air travel?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/09
No data
02/09
No data
Today
No data
04/09
US$107
05/09
No data
06/09
No data
07/09
No data
08/09
No data
busbud logoThe cheapest trip from St. Louis to Spartanburg was searched and found on 4 Sept 2025 with a price of US$107

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Spartanburg as early as possible.

You can expect to pay from US$107 to US$107 for a bus ticket from St. Louis to Spartanburg based on the last 2 days. You can expect to find the cheapest price for the trip at US$107, which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from St. Louis to Spartanburg but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from St. Louis to Spartanburg, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St. Louis to Spartanburg that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from St. Louis to Spartanburg, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from St. Louis to Spartanburg?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St. Louis by bus?

Bus from Spartanburg to St. Louis

You can also go to Spartanburg by train

Train from St. Louis to Spartanburg

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