Is there a way to reach Panama City from Boston without flying?

The bus is the best choice to get to Panama City without flying. Traveling by bus offers a budget-friendly, secure, and easy way to go between the two cities. Taking a ride with other travelers through carpool services is an additional option to consider.

How long does it take to get to Panama City from Boston by bus?

The travel time from Boston to Panama City is about 1d 18h, although the minimum time it takes to get there is 1d 16h with the fastest bus. This is the time it takes to travel the 1168 miles (1883 km) that separate the two cities.

What is the distance between Boston and Panama City?

About 1168 miles (1883 km) separate Boston and Panama City.

What are the departure and arrival stations when taking the bus from Boston to Panama City?

If you're headed to Panama City from Boston, chances are that your bus will leave from South Station and arrive at Panama City Greyhound Bus Station. These are the main pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.

What is the most cost-effective way to go from Boston to Panama City?

You can save a lot of money on your trip from Boston to Panama City by choosing to travel by bus. The lowest tickets for this trip cost as little as $261.

What is the ticket price for the bus trip from Boston to Panama City?

The average price of a one-way ticket from Boston to Panama City is $283. Over the last 30 days, the prices ranged between $261 and $403, so make sure to compare them to get the best option.

What are the best sights and things to do in Panama City?

Once in Panama City, you can start exploring the city and discover its surroundings. The top sights and things to do are Jungle Land Panama, The Biomuseo, Amador Causeway, Panama Viejo and The Panama Canal.

Is it possible to travel by overnight bus from Boston to Panama City?

Yes, you can take a night bus to go from Boston to Panama City. Don't forget to bring a snack and a blanket to help you stay comfortable through the night.

Boston (MA), US to Panama City, US Bus Tickets

TomorrowJun 2

from $279

TueJun 3

WedJun 4

ThuJun 5

FriJun 6

SatJun 7

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MonJun 9

Cheap buses leaving tomorrow

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: June 2 at 1:45pm
Departure city: Boston
Departure location: 151 Steel Pl, Cambridge
Arrival time: June 4 at 12:35pm
Destination city: Panama City
Destination location: Panama City Beach Station
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 23h
This trip is recommended because it is: Fastest
Departure time: June 2 at 7:35pm
Departure city: Boston
Departure location: Boston (South Station)
Arrival time: June 4 at 12:35pm
Destination city: Panama City
Destination location: Panama City Beach Station
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 18h
Departure time: June 2 at 7:35pm
Departure city: Boston
Departure location: Boston (South Station)
Arrival time: June 4 at 12:35pm
Destination city: Panama City
Destination location: Panama City Beach Station
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 18h

Accepted payments

Bus Boston to Panama City: Trip Overview

Average ticket price$283

Average bus trip duration1d 18h

Number of daily buses3

Earliest bus departure1:45pm

Distance1169 miles (1884 km)

Latest bus departure8:55pm

Compare bus companies

Greyhound

3.5/587,016 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/58,858 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Boston to Panama City Bus

Busbud helps you find a bus from Boston to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Boston to Panama City will be provided by the most trusted bus companies.

Discover how much the bus trip from Boston to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Boston and Panama City?

Stops in Boston

A - South Station

B - Back Bay Station

C - North Station

D - Copley Square

E - Prudential MBTA Station

F - Copley MBTA Station

Stops in Panama City

A - Panama City Greyhound Bus Station

Frequently asked questions for your trip Boston (MA), US - Panama City, US

Is there a way to reach Panama City from Boston without flying?
How long does it take to get to Panama City from Boston by bus?
What is the distance between Boston and Panama City?
What are the departure and arrival stations when taking the bus from Boston to Panama City?
What is the most cost-effective way to go from Boston to Panama City?
What is the ticket price for the bus trip from Boston to Panama City?
What are the best sights and things to do in Panama City?
Is it possible to travel by overnight bus from Boston to Panama City?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

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Today

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06/02

$289

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The cheapest trip from Boston to Panama City was searched and found on Jun 2, 2025 with a price of $289

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston to Panama City, as early as possible.

You can expect to pay from $289 to $289 for a bus ticket from Boston to Panama City based on the last 2 days. You can expect to find the cheapest price for the trip at $289 which is on 2025-06-02.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Boston and Panama City!

Much more than a mere vehicle taking you from Boston to Panama City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Boston to Panama City will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Boston to Panama City while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Will you be returning to Boston by bus?

Bus from Boston to Panama City

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Boston (MA), US to Panama City, US

Cheap buses leaving tomorrow

One passenger / one way

Bus Boston to Panama City: Trip Overview

Compare bus companies

Boston to Panama City Bus

Where are the popular stops in Boston and Panama City?

Frequently asked questions for your trip Boston (MA), US - Panama City, US

Is there a way to reach Panama City from Boston without flying?

How long does it take to get to Panama City from Boston by bus?

What is the distance between Boston and Panama City?

What are the departure and arrival stations when taking the bus from Boston to Panama City?

What is the most cost-effective way to go from Boston to Panama City?

What is the ticket price for the bus trip from Boston to Panama City?

What are the best sights and things to do in Panama City?

Is it possible to travel by overnight bus from Boston to Panama City?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

Will you be returning to Boston by bus?

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

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