Bus Tickets from Cheyenne to Des Moines

Previously seen trips

Next departures for Cheyenne to Des Moines on November 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    		Rodeway Inn Bus Stop
    		Des Moines (Subway)No tags
    FlixBus + Greyhound
      		Rodeway Inn Bus Stop
      		Des Moines (Subway)No tags
      FlixBus + Greyhound
        		Rodeway Inn Bus Stop
        		Des Moines (Subway)No tags
        Greyhound + FlixBus
          		Rodeway Inn Bus Stop
          		Des Moines (Subway)No tags
          Greyhound
            		Rodeway Inn Bus Stop
            		Des MoinesNo tags

            Accepted payments

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            • American Express
            • China Union Pay
            • Diners Club Canada
            • Discover Click to Pay
            • JCB payment
            • Klarna (Pay over time)
            • Google Pay

            Get from Cheyenne to Des Moines

            This route is served by bus only

            The journey takes about 15 hours 35 minutes and with fares starting at just $133, it presents an excellent value for a comfortable ride.

            1bus per day
            15h 35mAverage Duration
            584 milesDistance
            24kgCO₂ emissions

            Bus Cheyenne to Des Moines: Trip Overview

            Average ticket price$133
            Average bus trip duration15h 35m
            Number of daily buses1
            Earliest bus departure4:20pm
            Distance583 miles (940 km)

            Cheyenne to Des Moines Bus

            With Busbud, comparing and booking tickets for a bus from Cheyenne to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            We make sure you can find a bus service from Cheyenne to Des Moines from the most reliable bus companies operating this trip.

            From cheap bus tickets to more luxurious buses traveling from Cheyenne to Des Moines, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions for your trip Cheyenne - Des Moines

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            10/30
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            10/31
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            Today
            $143
            11/02
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            11/03
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            11/04
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            11/05
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            11/06
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            busbud logoThe cheapest trip from Cheyenne to Des Moines was searched and found on Nov 1, 2025 with a price of $143

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cheyenne to Des Moines, as early as possible.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while traveling from Cheyenne to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from Cheyenne to Des Moines, get comfy and count the stars.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Cheyenne to Des Moines that are otherwise impossible to come by with a plane.

            Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Cheyenne to Des Moines.

            Did you know?

            One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

            Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

            The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

            Will you be returning to Cheyenne by bus?

            Bus from Des Moines to Cheyenne

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