Bus Tickets from Des Moines, IA to San Antonio, TX

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TodayMay 19
TomorrowMay 20
from $227
WedMay 21
from $232
ThuMay 22
FriMay 23
SatMay 24
SunMay 25
MonMay 26

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: May 20 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: May 21 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc. + Greyhound Lines Mexico
    Greyhound Lines, Inc. + Greyhound Lines Mexico
    Vehicle: BusDuration:

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Bus Des Moines to San Antonio: Trip Overview

Average ticket price$227
Average bus trip duration1d 18h
Number of daily buses1
Earliest bus departure5:30am
Distance883 miles (1423 km)

Des Moines to San Antonio Bus

Busbud helps you find a bus from Des Moines to San Antonio. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Des Moines to San Antonio.

From cheap bus tickets to more luxurious buses traveling from Des Moines to San Antonio, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Des Moines - San Antonio

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and San Antonio!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Des Moines to San Antonio.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Des Moines to San Antonio that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Des Moines to San Antonio, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Des Moines by bus?

Bus from Des Moines to San Antonio

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