Bus Tickets from Indianapolis, IN to San Antonio, TX

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TodayMay 14
from $175
TomorrowMay 15
FriMay 16
SatMay 17
SunMay 18
MonMay 19
TueMay 20
WedMay 21

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 14 at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: May 16 at
    Destination city: San Antonio
    Destination location: Pearl District
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 14 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: May 15 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc. + Valley Transit Co., Inc.
    Greyhound Lines, Inc. + Valley Transit Co., Inc.
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: May 15 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc. + Valley Transit Co., Inc.
    Greyhound Lines, Inc. + Valley Transit Co., Inc.
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: May 15 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc. + Greyhound Lines Mexico
    Greyhound Lines, Inc. + Greyhound Lines Mexico
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: May 16 at
    Destination city: San Antonio
    Destination location: Pearl District
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from Indianapolis to San Antonio.

Bus
Average Price$125 - $288Average Duration1d 6h
40kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$325 - $325Average Duration1d 18h
146kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Indianapolis to San Antonio

Among the sustainable travel choices, the bus stands out as the good way to reach San Antonio. The journey takes about 1 day, 6 hours 25 minutes and with fares starting at just $125, it presents an excellent value for a comfortable ride.

7bus per day
1d 6hAverage Duration
$125Cheapest ticket
40kgCO₂ emissions

Bus Indianapolis to San Antonio: Trip Overview

Average ticket price$197
Average bus trip duration1d 6h
Number of daily buses7
Earliest bus departure3:15am
Distance997 miles (1607 km)
Latest bus departure11:55pm

Indianapolis to San Antonio Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Indianapolis to San Antonio.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to San Antonio.

From cheap bus tickets to more luxurious buses traveling from Indianapolis to San Antonio, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Indianapolis - San Antonio

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/12
No data
05/13
No data
Today
No data
05/15
No data
05/16
No data
05/17
No data
05/18
$239
05/19
No data
busbud logoThe cheapest trip from Indianapolis to San Antonio was searched and found on May 18, 2025 with a price of $239

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to San Antonio, as early as possible.

You can expect to pay from $239 to $460 for a bus ticket from Indianapolis to San Antonio based on the last 2 days. You can expect to find the cheapest price for the trip at $239 which is on 2025-05-18.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Indianapolis to San Antonio but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Indianapolis to San Antonio.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Indianapolis to San Antonio that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Indianapolis to San Antonio, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Indianapolis to San Antonio?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to San Antonio

You can also go to San Antonio by train

Train from Indianapolis to San Antonio

Why choose Busbud?

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