Next bus departures

Next departures for Jacksonville to Chicago on October 2
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	11:15pm	Jacksonville Bus Station	1d 12h	11:05am	Chicago 95Th & Dan Ryan	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:25pm	Jacksonville Bus Station	23h 45m	8:10pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	11:15pm	Jacksonville Bus Station	1d 10h	8:25am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	11:15pm	Jacksonville Bus Station	1d 9h	8:00am	537-517 W. Jackson Blvd	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:25pm	Jacksonville Bus Station	1d 3h	11:30pm	Chicago 95Th & Dan Ryan	No tags

Next departures for Jacksonville to Chicago on October 3
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus Wifi Toilet Power outlets	9:30am	Jacksonville Bus Station	1d 2h	11:05am	Chicago 95Th & Dan Ryan	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	4:30pm	Jacksonville Bus Station	23h 45m	3:15pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:05am	Jacksonville Bus Station	1d	8:25am	Downtown Greyhound Station	No tags
	Bus Wifi Toilet Power outlets	9:30am	Jacksonville Bus Station	1d 5h	1:45pm	537-517 W. Jackson Blvd	No tags
Greyhound Lines, Inc. + FlixBus	Bus Wifi Toilet Power outlets	9:30am	Jacksonville Bus Station	1d 3h	11:30am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:25pm	Jacksonville Bus Station	23h 45m	8:10pm	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	11:15pm	Jacksonville Bus Station	1d 10h	8:25am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:05am	Jacksonville Bus Station	23h 55m	8:00am	537-517 W. Jackson Blvd	No tags

Next departures for Jacksonville to Chicago on October 5
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	4:30pm	Jacksonville Bus Station	1d 2h	6:25pm	Chicago 95Th & Dan Ryan	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	4:30pm	Jacksonville Bus Station	23h 45m	3:15pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:05am	Jacksonville Bus Station	1d	8:25am	Downtown Greyhound Station	No tags
	Bus Wifi Toilet Power outlets	9:30am	Jacksonville Bus Station	1d 5h	1:45pm	537-517 W. Jackson Blvd	No tags
Greyhound Lines, Inc. + FlixBus	Bus Wifi Toilet Power outlets	9:30am	Jacksonville Bus Station	1d 3h	11:30am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:25pm	Jacksonville Bus Station	23h 45m	8:10pm	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	11:15pm	Jacksonville Bus Station	1d 10h	8:25am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:05am	Jacksonville Bus Station	23h 55m	8:00am	537-517 W. Jackson Blvd	No tags

Next departures for Jacksonville to Chicago on October 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	4:30pm	Jacksonville Bus Station	1d 2h	6:25pm	Chicago 95Th & Dan Ryan	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	4:30pm	Jacksonville Bus Station	23h 45m	3:15pm	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:05am	Jacksonville Bus Station	1d	8:25am	Downtown Greyhound Station	No tags
	Bus Wifi Toilet Power outlets	9:30am	Jacksonville Bus Station	1d 5h	1:45pm	537-517 W. Jackson Blvd	No tags
Greyhound Lines, Inc. + FlixBus	Bus Wifi Toilet Power outlets	9:30am	Jacksonville Bus Station	1d 3h	11:30am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:25pm	Jacksonville Bus Station	23h 45m	8:10pm	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	11:15pm	Jacksonville Bus Station	1d 10h	8:25am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:05am	Jacksonville Bus Station	23h 55m	8:00am	537-517 W. Jackson Blvd	No tags

Last refresh of the prices: Yesterday at 9:38 PM EDT.

Compare 2 ways to go from Jacksonville to Chicago

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Chicago. The journey takes about 1 day, 2 hours 35 minutes and with fares starting at just ARS 148,703, it presents an excellent value for a comfortable ride.

18bus per day

1d 2hAverage Duration

860 milesDistance

35kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceARS 148,703 - ARS 533,215	Average Duration1d 2h	CO₂ emissions 35kg CO₂e
Train	Average PriceARS 210,582 - ARS 3,536,563	Average Duration1d 17h	CO₂ emissions 126kg CO₂e

Bus stations and stops in Jacksonville and Chicago

Stops in Jacksonville

A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA
Visit page
B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA
C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207
D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

Greyhound

3.5/588,196 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound Jacksonville Chicago recent customer reviews

Solo la demora en una de las estaciones que por conexión me ocasionó otra demora y llegue muy tarde a mi destino final

Fernando S.

December 8, 2017

FlixBus

3.5/516,015 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, Greyhound, Futura, Tufesa, Chihuahuenses, Adirondack Trailways, Valley Transit

Frequently asked questions about traveling from Jacksonville, FL to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Jacksonville to Chicago?
The cheapest bus tickets from Jacksonville to Chicago start from ARS 148,703. The average price for this route is around ARS 217,491. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to Chicago?
The average bus trip duration from Jacksonville to Chicago is 1d 2h, covering a distance of 860 miles (1387 km). The quickest bus can get you there in 1d and is operated by FlixBus.
Which bus companies service the Jacksonville to Chicago route?
Several major bus companies operate on this route with 18 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Jacksonville to Chicago?
The earliest bus departs from Jacksonville to Chicago at 9:05am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Jacksonville to Chicago?
A bus trip from Jacksonville to Chicago generates an estimated 34.6616 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Jacksonville to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88188 reviews.
Which bus company has the best Wi-Fi from Jacksonville to Chicago?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Jacksonville to Chicago?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to Chicago?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/30

ARS 343,827

10/01

ARS 317,256

Today

ARS 353,205

10/03

ARS 354,768

10/04

ARS 204,721

10/05

ARS 201,595

10/06

ARS 151,579

10/07

ARS 195,343

The cheapest trip from Jacksonville, FL to Chicago was searched and found on Oct 6, 2026 with a price of ARS 151,579

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Chicago, as early as possible.

You can expect to pay from ARS 151,579 to ARS 354,768 for a bus ticket from Jacksonville, FL to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at ARS 151,579 which is on 2026-10-06.