Bus Tickets from Orlando to San Diego, CA, US

Previously seen trips

Next departures for Orlando to San Diego on November 24
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Bus
Orlando Bus Station
Balboa ParkNo tags
Greyhound + FlixBus
Bus
Orlando Bus Station
San Diego (Old Town-FlixBus)No tags
Greyhound + FlixBus
Bus
Orlando Bus Station
UCSD Health La Jolla StationNo tags
FlixBus + Greyhound
Bus
Orlando Bus Station
Downtown SD (Seaport)No tags
FlixBus + Greyhound
Bus
Orlando Bus Station
5716 Hardy AveNo tags

Compare 2 ways to go from Orlando to San Diego

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach San Diego. The journey takes about 2 days, 16 hours 50 minutes and with fares starting at just $172, it presents an excellent value for a comfortable ride.

11bus per day
2d 16hAverage Duration
2133 milesDistance
86kgCO₂ emissions
Average Price$172 - $622Average Duration2d 16h
86kg CO₂e
Average Price$555 - $686Average Duration4d 2h
313kg CO₂e

Frequently asked questions about traveling from Orlando to San Diego, CA, US by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/22
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11/23
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Today
$159
11/25
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11/26
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11/27
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11/28
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11/29
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busbud logoThe cheapest trip from Orlando to San Diego, CA, US was searched and found on Nov 24, 2025 with a price of $159

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to San Diego, CA, US, as early as possible.

What's the cheapest way to go from Orlando to San Diego, CA, US?

busbud logoThe bus is the cheapest travel choice for this destination

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