Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Pittsburgh Intermodal Station | 409 Townsend St, SF | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Pittsburgh Intermodal Station | 409 Townsend St, SF | No tags | ||||
 | Bus | Pittsburgh Intermodal Station | San Francisco Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Pittsburgh Intermodal Station | 409 Townsend St, SF | No tags |
Last refresh of the prices: Last Thursday at 11:34 PM EST.
Get from Pittsburgh to San Francisco
The journey takes about 2 days, 23 hours 25 minutes and with fares starting at just $240, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pittsburgh and San Francisco?
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
Stops in San Francisco
- A
Hyde/Beach (Fisherman's Wharf)
700 Beach Street, San Francisco, CA 94109, USA - B
Powell Station
25 Cyril Magnin St , San Francisco, CA 94102-2812 - C
Union Square Hilton
255 Mason St,, San Francisco, CA 94102-2114 - D
San Francisco Greyhound Station
200 Folsom St, San Francisco, CA 94105 - E
444 Townsend St.
444 Townsend St, San Francisco, CA 94107, USA
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Pittsburgh to San Francisco, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Pittsburgh to San Francisco?
The cheapest bus tickets from Pittsburgh to San Francisco start from $240. The average price for this route is around $506. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pittsburgh to San Francisco?
The average bus trip duration from Pittsburgh to San Francisco is 2d 23h, covering a distance of 2255 miles (3636 km). The quickest bus can get you there in 2d 14h and is operated by Greyhound.
Which bus companies service the Pittsburgh to San Francisco route?
Several major train operators operate on this route with 3 trains available per day.
What is the earliest and latest departure time for the bus from Pittsburgh to San Francisco?
The earliest bus departs from Pittsburgh to San Francisco at 1:35am. And the latest bus departs at 8:00pm.
What are the CO₂ emissions for the bus trip from Pittsburgh to San Francisco?
A bus trip from Pittsburgh to San Francisco generates an estimated 91 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pittsburgh to San Francisco, US was searched and found on Jan 11, 2026 with a price of $410To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to San Francisco, US, as early as possible.
You can expect to pay from $410 to $586 for a bus ticket from Pittsburgh to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at $410 which is on 2026-01-11.
Top traveled bus routes
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