Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Salisbury (Citgo Fast Stop) | Syracuse (Regional Transportation Center) | No tags | ||||
| Bus | Salisbury (Citgo Fast Stop) | Syracuse (Regional Transportation Center) | No tags | ||||
FlixBus + Greyhound | Bus | Salisbury (Citgo Fast Stop) | Syracuse (Regional Transportation Center) | No tags | ||||
| Bus | Salisbury (Citgo Fast Stop) | Syracuse (Regional Transportation Center) | No tags | ||||
| Bus | Salisbury (Citgo Fast Stop) | Syracuse (Regional Transportation Center) | No tags |
Compare 2 ways to go from Salisbury to Syracuse
Among the sustainable travel choices, the Bus stands out as a good way to reach Syracuse. The journey takes about 21 hours 40 minutes and with fares starting at just $133, it presents an excellent value for a comfortable ride.
Where are the popular stops in Salisbury and Syracuse?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Salisbury, NC, US to Syracuse, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Salisbury to Syracuse?
The cheapest bus tickets from Salisbury to Syracuse start from $133. The average price for this route is around $209. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Salisbury to Syracuse?
The average bus trip duration from Salisbury to Syracuse is 21h 40m, covering a distance of 558 miles (899 km). The quickest bus can get you there in 21h 40m and is operated by Greyhound.
Which bus companies service the Salisbury to Syracuse route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Salisbury to Syracuse?
The earliest bus departs from Salisbury to Syracuse at 6:15am. And the latest bus departs at 6:45pm.
What are the CO₂ emissions for the bus trip from Salisbury to Syracuse?
A bus trip from Salisbury to Syracuse generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Salisbury, NC, US to Syracuse, US was searched and found on Feb 11, 2026 with a price of $227To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury, NC, US to Syracuse, US, as early as possible.
What's the cheapest way to go from Salisbury, NC, US to Syracuse, US?
The Bus is the cheapest travel choice for this destination
