Bus Tickets from St Louis, MO to Charlotte, NC

Find affordable bus tickets from St Louis, MO to Charlotte, NC with flexible options. Book your trip now

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TodayMay 20
TomorrowMay 21
from $104
ThuMay 22
from $92
FriMay 23
from $100
SatMay 24
SunMay 25
MonMay 26
TueMay 27

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 21 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 22 at
    Destination city: Charlotte
    Destination location: Charlotte Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 21 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 22 at
    Destination city: Charlotte
    Destination location: Charlotte Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 21 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 21 at
    Destination city: Charlotte
    Destination location: Charlotte Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 21 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 22 at
    Destination city: Charlotte
    Destination location: Charlotte Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 21 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 22 at
    Destination city: Charlotte
    Destination location: Charlotte Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from St Louis to Charlotte.

Bus
Average Price$76 - $177Average Duration19h 30m
23kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$246 - $246Average Duration1d 17h
83kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St Louis to Charlotte

Among the sustainable travel choices, the bus stands out as the good way to reach Charlotte. The journey takes about 19 hours 30 minutes and with fares starting at just $76, it presents an excellent value for a comfortable ride.

7bus per day
19h 30mAverage Duration
$76Cheapest ticket
23kgCO₂ emissions

Bus St Louis to Charlotte: Trip Overview

Average ticket price$86
Average bus trip duration19h 30m
Number of daily buses7
Earliest bus departure1:40am
Distance567 miles (913 km)
Latest bus departure7:00pm

St Louis to Charlotte Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from St Louis to Charlotte.

We make it our job to connect you with the most dependable bus companies that cover bus service from St Louis to Charlotte.

From cheap bus tickets to more luxurious buses traveling from St Louis to Charlotte, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip St Louis - Charlotte

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/18
No data
05/19
$175
Today
No data
05/21
$104
05/22
$92
05/23
$100
05/24
$78
05/25
$103
busbud logoThe cheapest trip from St Louis to Charlotte was searched and found on May 24, 2025 with a price of $78

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to Charlotte, as early as possible.

You can expect to pay from $78 to $200 for a bus ticket from St Louis to Charlotte based on the last 2 days. You can expect to find the cheapest price for the trip at $78 which is on 2025-05-24.

Usually Greyhound Lines, Inc., FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from St Louis to Charlotte but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from St Louis to Charlotte.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St Louis to Charlotte that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from St Louis to Charlotte while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from St Louis to Charlotte?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St Louis by bus?

Bus from St Louis to Charlotte

You can also go to Charlotte by train

Train from St Louis to Charlotte

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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