Bus Tickets from Tupelo to Detroit, MI

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TodaySep 2
from $146
TomorrowSep 3
from $112
ThuSep 4
from $111
FriSep 5
from $104
SatSep 6
SunSep 7
MonSep 8
TueSep 9

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: September 3 at
    Departure city: Tupelo
    Departure location: Tupelo (Brothers Quick Stop)
    Arrival time: September 4 at
    Destination city: Detroit
    Destination location: Detroit Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: September 3 at
    Departure city: Tupelo
    Departure location: Tupelo (Brothers Quick Stop)
    Arrival time: September 4 at
    Destination city: Detroit
    Destination location: Detroit Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Tupelo
    Departure location: Tupelo (Brothers Quick Stop)
    Arrival time: September 4 at
    Destination city: Detroit
    Destination location: Detroit Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Tupelo to Detroit, MI: Trip Overview

Average ticket price$151
Average bus trip duration1d
Number of daily buses1
Earliest bus departure10:55am
Distance636 miles (1025 km)
Latest bus departure9:35pm

Tupelo to Detroit Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Tupelo to Detroit.

Bus service from Tupelo to Detroit will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Tupelo to Detroit, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Tupelo - Detroit, MI

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/31
$166
09/01
$182
Today
$138
09/03
$105
09/04
$104
09/05
$97
09/06
No data
09/07
No data
busbud logoThe cheapest trip from Tupelo to Detroit, MI was searched and found on Sep 5, 2025 with a price of $97

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Detroit, MI, as early as possible.

You can expect to pay from $97 to $193 for a bus ticket from Tupelo to Detroit, MI based on the last 2 days. You can expect to find the cheapest price for the trip at $97 which is on 2025-09-05.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Tupelo to Detroit but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Tupelo to Detroit, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Tupelo to Detroit that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Tupelo to Detroit, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Tupelo by bus?

Bus from Detroit, MI to Tupelo

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