Bus Tickets from Greenville, SC to Winston-Salem

Previously seen trips

Next departures for Greenville to Winston-Salem on October 11
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
1116 Woodruff Rd
Winston Salem Greyhound Bus StationNo tags
Greyhound
1116 Woodruff Rd
Winston Salem Greyhound Bus StationNo tags
Greyhound
1116 Woodruff Rd
Winston Salem Greyhound Bus StationNo tags
Greyhound
1116 Woodruff Rd
Winston Salem Greyhound Bus StationNo tags
Greyhound
1116 Woodruff Rd
Winston Salem Greyhound Bus StationNo tags

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Bus Greenville, SC to Winston-Salem: Trip Overview

Average Ticket PriceUS$153
Average Bus Trip Duration3h 55m
Number of daily buses4
Earliest bus departure10:50am
Distance241 km
Latest bus departure10:00pm

Greenville to Winston-Salem Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Winston-Salem is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Greenville to Winston-Salem will be provided by the most trusted bus companies.

Discover how much the bus trip from Greenville to Winston-Salem will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville, SC - Winston-Salem

  1. What is the distance between Greenville and Winston-Salem?

    The distance between Greenville and Winston-Salem is around 240 km (149 miles).

  2. What are the departure and arrival locations for buses traveling from Greenville to Winston-Salem?

    Buses traveling this route start their trip at Guadalajara Supermarket Bus Stop, in Greenville, and end it at Winston Salem Greyhound Bus Station, in Winston-Salem.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-09
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Today
US$33
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busbud logoThe cheapest trip from Greenville, SC to Winston-Salem was searched and found on Oct 11, 2025 with a price of US$33

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Winston-Salem, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Greenville to Winston-Salem.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Greenville to Winston-Salem, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Winston-Salem will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Winston-Salem while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Greenville, SC by bus?

Bus from Winston-Salem to Greenville, SC

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