Bus Tickets from San Antonio (TX), US to Greenville (SC)

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Compare 2 ways to go from San Antonio to Greenville

Bus
Average PriceUS$109 - US$281Average Duration1d 5h
41kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$204 - US$642Average Duration2d 21h
148kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Antonio to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 5 hours 30 minutes, and with fares starting at just US$109, it presents an excellent value for a comfortable ride.

5bus per day
1d 5hAverage Duration
US$109Cheapest ticket
41kgCO₂ emissions

Bus San Antonio to Greenville: Trip Overview

Average Ticket PriceUS$150
Average Bus Trip Duration1d 5h
Number of daily buses5
Earliest bus departure1:05am
Distance1636 km
Latest bus departure9:00pm

San Antonio to Greenville Bus

With Busbud, comparing and booking tickets for a bus from San Antonio to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Antonio to Greenville from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from San Antonio to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Antonio (TX), US - Greenville (SC)

  1. How long does it take to get to Greenville from San Antonio by bus?

    The bus ride from San Antonio to Greenville takes 1d 5h, on average. For the shortest travel time, select the fastest bus available, which will take you to Greenville in about 23h 40m.

  2. What is the distance between San Antonio and Greenville?

    San Antonio and Greenville are 1631 km (1012 miles) apart.

  3. What are the departure and arrival locations for buses traveling from San Antonio to Greenville?

    Buses departing from San Antonio Bus Station in San Antonio will take you to Guadalajara Supermarket Bus Stop in Greenville.

  4. What is the cheapest way to get from San Antonio to Greenville?

    The least expensive option to go from San Antonio to Greenville would be going by bus. The ticket price for this bus starts at US$109, making this your best choice for this trip.

  5. How much is the bus from San Antonio to Greenville?

    The bus from San Antonio to Greenville will cost you US$150, on average.

  6. Is it possible to travel by overnight bus from San Antonio to Greenville?

    Yes! If you're heading from San Antonio to Greenville, you'll find buses departing until 9:00pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-26
US$252
05-27
No data
Today
No data
05-29
No data
05-30
No data
05-31
US$222
06-01
No data
06-02
US$125
busbud logoThe cheapest trip from San Antonio to Greenville was searched and found on Jun 2, 2025 with a price of US$125

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio to Greenville, as early as possible.

You can expect to pay from US$125 to US$252 for a bus ticket from San Antonio to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at US$125 which is on 2025-06-02.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Antonio to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Antonio to Greenville, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Antonio to Greenville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from San Antonio to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from San Antonio to Greenville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Antonio by bus?

Bus from San Antonio to Greenville

You can also go to Greenville by train

Train from San Antonio to Greenville

Why choose Busbud?

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