Bus Tickets from Greenville (SC) to San Antonio (TX), US

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TodayMay 30
TomorrowMay 31
from US$175
SunJun 1
MonJun 2
TueJun 3
WedJun 4
ThuJun 5
FriJun 6

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 31 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 2 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
    FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 31 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 1 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
    FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 1 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc. + Valley Transit
    FlixBus + Greyhound Lines, Inc. + Valley Transit
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 1 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
    FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: June 1 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Tuesday at 3:15 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
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  • JCB payment
  • Klarna (Pay over time)
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Compare 2 ways to go from Greenville to San Antonio

Bus
Average PriceUS$92 - US$247Average Duration1d 3h
41kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$249 - US$634Average Duration1d 19h
148kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to San Antonio

Among the sustainable travel choices, the bus stands out as a good way to reach San Antonio. The journey takes about 1 day, 3 hours 35 minutes, and with fares starting at just US$92, it presents an excellent value for a comfortable ride.

5bus per day
1d 3hAverage Duration
US$92Cheapest ticket
41kgCO₂ emissions

Bus Greenville to San Antonio: Trip Overview

Average Ticket PriceUS$124
Average Bus Trip Duration1d 3h
Number of daily buses5
Earliest bus departure8:45am
Distance1636 km
Latest bus departure10:00pm

Greenville to San Antonio Bus

Busbud helps you find a bus from Greenville to San Antonio. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Greenville to San Antonio from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to San Antonio will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville (SC) - San Antonio (TX), US

  1. How long does it take to get to San Antonio from Greenville by bus?

    The bus ride from Greenville to San Antonio takes 1d 3h, on average. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 1d 2h.

  2. What is the distance between Greenville and San Antonio?

    Greenville and San Antonio are 1631 km (1012 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Greenville to San Antonio?

    Buses departing from Guadalajara Supermarket Bus Stop in Greenville will take you to San Antonio Bus Station in San Antonio.

  4. What is the cheapest way to get from Greenville to San Antonio?

    If you're on a budget, consider traveling by bus to San Antonio from Greenville; it tends to be more affordable. The ticket price for this bus starts at US$92, making this your best choice for this trip.

  5. How much is the bus from Greenville to San Antonio?

    The bus from Greenville to San Antonio will cost you US$124, on average.

  6. Is it possible to travel by overnight bus from Greenville to San Antonio?

    Yes! If you're heading from Greenville to San Antonio, you'll find buses departing until 10:00pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-28
No data
05-29
No data
Today
No data
05-31
US$208
06-01
No data
06-02
No data
06-03
No data
06-04
No data
busbud logoThe cheapest trip from Greenville to San Antonio was searched and found on May 31, 2025 with a price of US$208

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to San Antonio, as early as possible.

You can expect to pay from US$208 to US$208 for a bus ticket from Greenville to San Antonio based on the last 2 days. You can expect to find the cheapest price for the trip at US$208 which is on 2025-05-31.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and San Antonio!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to San Antonio, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to San Antonio will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Greenville to San Antonio, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Greenville to San Antonio?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville by bus?

Bus from Greenville to San Antonio

You can also go to San Antonio by train

Train from Greenville to San Antonio

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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