Bus Tickets from Greenville, SC to San Antonio, US

Previously seen trips

Next departures for Greenville to San Antonio on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
1116 Woodruff Rd
San Antonio Bus StationNo tags
Greyhound
1116 Woodruff Rd
San Antonio Bus StationNo tags
FlixBus + Greyhound
1116 Woodruff Rd
Pearl DistrictNo tags
Greyhound + FlixBus
1116 Woodruff Rd
San Antonio Bus StationNo tags
FlixBus + Valley Transit + Greyhound
1116 Woodruff Rd
San Antonio Bus StationNo tags

Accepted payments

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  • China Union Pay
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Compare 2 ways to go from Greenville to San Antonio

Bus
Average PriceUS$104 - US$192Average Duration1d 4h
41kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$214 - US$574Average Duration1d 19h
148kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to San Antonio

Among the sustainable travel choices, the bus stands out as a good way to reach San Antonio. The journey takes about 1 day, 4 hours 20 minutes, and with fares starting at just US$104, it presents an excellent value for a comfortable ride.

5bus per day
1d 4hAverage Duration
US$104Cheapest ticket
41kgCO₂ emissions

Bus Greenville, SC to San Antonio, US: Trip Overview

Average Ticket PriceUS$127
Average Bus Trip Duration1d 4h
Number of daily buses5
Earliest bus departure1:25pm
Distance1636 km
Latest bus departure10:00pm

Greenville to San Antonio Bus

Busbud helps you find a bus from Greenville to San Antonio. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Greenville to San Antonio from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to San Antonio will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville, SC - San Antonio, US

  1. What is the distance between Greenville and San Antonio?

    Greenville and San Antonio are 1631 km (1012 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Greenville to San Antonio?

    Buses departing from Guadalajara Supermarket Bus Stop in Greenville will take you to San Antonio Bus Station in San Antonio.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-10
US$150
10-11
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Today
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10-13
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10-14
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10-15
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10-16
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10-17
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busbud logoThe cheapest trip from Greenville, SC to San Antonio, US was searched and found on Oct 10, 2025 with a price of US$150

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to San Antonio, US, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and San Antonio!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to San Antonio, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to San Antonio will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Greenville to San Antonio, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Greenville, SC to San Antonio, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from San Antonio, US to Greenville, SC

You can also go to San Antonio, US by train

Train from Greenville, SC to San Antonio, US

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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