Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Spartanburg | Harrisburg Bus Station | No tags | |||||
| Spartanburg | Harrisburg Bus Station | No tags | |||||
FlixBus + Greyhound | Spartanburg | Harrisburg Bus Station | No tags | |||||
| Spartanburg | Harrisburg Bus Station | No tags | |||||
| Spartanburg | Harrisburg Bus Station | No tags |
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Compare 2 ways to go from Spartanburg to Harrisburg
Among the sustainable travel choices, the train stands out as a good way to reach Harrisburg. The journey takes about 16 hours 21 minutes, and with fares starting at just US$194, it presents an excellent value for a comfortable ride.
Bus Spartanburg to Harrisburg: Trip Overview
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Spartanburg to Harrisburg Bus
With Busbud, comparing and booking tickets for a bus from Spartanburg to Harrisburg is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Spartanburg to Harrisburg will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Spartanburg to Harrisburg, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Spartanburg and Harrisburg?
Frequently asked questions on the trip Spartanburg - Harrisburg
What is the travel distance from Spartanburg to Harrisburg?
It's about 741 km (460 miles) from Spartanburg to Harrisburg.
What are the departure and arrival locations for buses traveling from Spartanburg to Harrisburg?
Buses traveling this route start their trip at Super Acapulco, in Spartanburg, and end it at Harrisburg Bieber Greyhound Station, in Harrisburg.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Spartanburg to Harrisburg was searched and found on Nov 2, 2025 with a price of US$232To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Spartanburg to Harrisburg, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Spartanburg to Harrisburg.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Spartanburg to Harrisburg, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Spartanburg to Harrisburg that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Spartanburg to Harrisburg while indulging in miles on end of beautiful scenic views.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
What's the cheapest way to go from Spartanburg to Harrisburg?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Spartanburg
Buses Leaving from Spartanburg
- Bus from Spartanburg to Greenville
- Bus Spartanburg - Greenville
- Spartanburg - Charlotte
- Bus from Spartanburg to Atlanta
- Bus Spartanburg - Knoxville
- Spartanburg - Charleston
- Bus from Spartanburg to Grand Rapids
- Bus Spartanburg - Washington
- Spartanburg - Oklahoma City
- Bus from Spartanburg to West Palm Beach
- Bus Spartanburg - Indianapolis
- Spartanburg - St. Louis
- Bus from Spartanburg to New York City
- Bus Spartanburg - Tyler
- Spartanburg - Newark
Buses Going to Spartanburg
- Bus from Greenville to Spartanburg
- Bus Greenville - Spartanburg
- El Paso - Spartanburg
- Bus from Burlington to Spartanburg
- Bus Orlando - Spartanburg
- Wilmington - Spartanburg
- Bus from New Orleans to Spartanburg
- Bus Cincinnati - Spartanburg
- New York City - Spartanburg
- Bus from Portland to Spartanburg
- Bus Los Angeles - Spartanburg
- Myrtle Beach - Spartanburg
- Bus from West Palm Beach to Spartanburg
- Bus Laredo - Spartanburg
- Miami - Spartanburg
Popular Buses Connecting Harrisburg
Buses Leaving from Harrisburg
- Bus from Harrisburg to Houston
- Bus Harrisburg - Baltimore
- Harrisburg - Temple
- Bus from Harrisburg to Allentown
- Bus Harrisburg - Chicago
- Harrisburg - Atlanta
- Bus from Harrisburg to Forest City
- Bus Harrisburg - Salt Lake City
- Harrisburg - Rockledge
- Bus from Harrisburg to Richmond
- Bus Harrisburg - Springfield
- Harrisburg - New Orleans
- Bus from Harrisburg to Newark
- Bus Harrisburg - Dover
- Harrisburg - San Diego
Buses Going to Harrisburg
- Bus from Pittsburgh to Harrisburg
- Bus Baltimore - Harrisburg
- Houston - Harrisburg
- Bus from Orlando to Harrisburg
- Bus Philadelphia - Harrisburg
- Indianapolis - Harrisburg
- Bus from Allentown to Harrisburg
- Bus New Haven - Harrisburg
- Salt Lake City - Harrisburg
- Bus from Latrobe to Harrisburg
- Bus New York City - Harrisburg
- Lawrence - Harrisburg
- Bus from Lewistown to Harrisburg
- Bus Wilkes-Barre - Harrisburg
- Columbus - Harrisburg
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Philadelphia to New York City
- Bus Niagara Falls - New York City
- Buffalo - New York City
- Bus from Baton Rouge to New Orleans
- Bus Baltimore - New York City
- Atlanta - Savannah
- Bus from Albany to New York City
- Bus New York City - Burlington
- Las Vegas - Los Angeles
- Bus from Detroit to Chicago
- Bus Los Angeles - San Diego
- Miami - Orlando